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A group of cells, which share a similar structure and function, and their ECM
Tissue
What functions to:
transport nutrients to the cells
remove waste products from cells
transport secretory products from the cells
Interstitial fluid
Functions in secretion, absorption, and excretion. Forms sheets which line the cavities of organs and cover the body surface. Also forms many glands.
Epithelial tissue
Supports the body and holds it together. Transports substances through the body and protects it from foreign invaders. Characterized by cells which produce abundant extracellular matrix.
Connective tissue
Formed of cells specialized for contraction and movement
Muscle tissue
Composed of cells with long, fine processes specialized for communication between various body structures and control and integration of their activities.
Nervous tissue
Tissue samples removed during medical procedures or surgery that are fixed in formalin and studied microscopically. If results are needed during surgery, the biopsy can be rapidly frozen using liquid nitrogen and be sectioned immediately.
Biopsy
Epithelial tissue arises from...
Ectoderm
Endoderm
Mesoderm
Functions of glandular epithelium
Protection
Sensory
Secretion
Absorption
Excretion
A thin, noncellular layer which attaches the epithelial tissue to underlying connective tissue
Basement membrane
Thin sheetlike layer to which the epithelial cells are attached
Basal lamina
Diffuse fibrous layer beneath the basal lamina
Reticular lamina
T/F: Epithelial tissues are avascular
True
1 multiple choice option
The layer of connective tissue which lies deep to the basement membrane of the epithelium lining the respiratory, digestive, and urinary system
Lamina propria
Describes part of an epithelial cell facing a cavity or space
Apical pole
Describes part of an epithelial cell resting on the basement membrane
Basal pole
Epithelial cells arranged in a single layer are classified as....
Simple
Epithelial cells arranged in multiple layers are classified as....
Stratified
Type of epithelium found in alveoli of lungs
Simple squamous
Type of epithelium found in lining of blood and lymph vessels
Simple squamous; endothelium
Type of epithelium found in membranes covers organs and the body walls
Simple squamous; mesothelium
Type of epithelium found in glands and ducts or kidney tubules
Simple cuboidal
Type of epithelium found in the stomach, intestines, and parts of the respiratory system
Simple columnar
Type of epithelium found in the uterus and uterine tubes
Simple columnar
Specialized structure found in columnar epithelium that contain large secretory vesicles which produce mucus
Goblet cells
Specialized structure found in columnar epithelium that contain microscopic fingerlike projections of the plasma membrane
Microvilli
Specialized structure found in columnar epithelium that are absorptive in function, much longer than microvilli, and may branch distally(found in the male reproductive system)
Stereocilia
Specialized structure found in columnar epithelium that appear as long microscopic hairlike processes which move material along a surface
Cilia
A specialized type of columnar epithelium which has only one layer of cells. Every cell touches the basement membrane but some cells do not reach the surface of the epithelium.
Pseudostratified
Type of epithelium found in the respiratory air passages(nasal cavity, trachea, bronchi)
Pseudostratified columnar
Type of epithelium found in the male reproductive system
Pseudostratified columnar
Stratified epithelia are classified based on the cell shape of the ______________ layer
Superficial; outermost
Stratified epithelium found in epidermis
Keratinized squamous
Stratified epithelium found in the mouth, pharynx, esophagus, and vagina
Nonkeratinized squamous
Stratified epithelium found in the sweat gland ducts and ovarian follicles
Cuboidal
Stratified epithelium found in the male urethra
Columnar
What type of epithelium is specialized for organs subject to stretch?
Transitional epithelium
In which organs is transitional epithelium found?
Ureters, urinary bladder
If the secretory portion of a gland is either short or long and coiled, it is classified as...
Tubular
If the secretory portion of a gland is rounded or saclike, it is classified as...
Acinar
Glands that secrete their product into ducts which open into a hollow organ or on a surface
Exocrine
Glands that secrete their product directly into the bloodstream
Endocrine
Sweat glands, salivary glands, and digestive glands of the stomach and pancreas are examples of...
Exocrine glands
Pituitary, thyroid, parathyroid, and suprarenal glands are examples of...
Endocrine glands
Type of exocrine gland in which secretory product collects in the cell which then ruptures to release it
Holocrine
Type of exocrine gland in which secretory product collects at the apex of the cell which is then pinched off, releasing the product into a duct
Apocrine
Type of exocrine gland in which secrete their product through the cell membrane without damage to the cell
Merocrine
Example of a holocrine gland
Sebaceous
Example of apocrine gland
Mammary
Example of merocrine gland
Salivary
Form a seal between adjacent cells; the most apical of the junctions
Tight junction; occluding junction
Sites of strong cell adhesion found immediately below tight junctions
Adherens junction
Anchoring junction which forms a single "spot-weld" and does not form a belt around the cell
Desmosome
Channel for communication between cells
Gap junction
Attach cells to the basal lamina
Hemidesmosome
Connective tissue consists mainly of an _______________ with relatively few cells embedded within it
ECM; extracellular matrix
In the embryo, connective tissue is derived from ____________, which in turn originates from mesoderm and neural crest cells.
Mesenchyme
In the embryo, connective tissue is derived from mesenchyme, which in turn originates from...
Mesoderm and neural crest cells
Four main functions of connective tissue
Attachment
Support
Transport
Defense
The most common cells found in connective tissue
Fibroblasts
Cells which develop from mesenchyme and are permanent residents of connective tissue. They function in tissue repair.
Fibroblasts
Fibroblasts secrete...
Collagen, elastin, all components of ground substance
Fat cells found in the connective tissue of many organs
Adipocytes
Phagocytic cells which are involved in turnover of protein fibers, and function to remove cellular debris, neoplastic cells, bacteria and other invaders
Macrophages
Cells that release mediators of inflammation such as histamine
Mast cells
Lymphocyte derived cells which produce antibodies and are involved in immune defense
Plasma cells
An allergy is a hypersensitivity reaction to an allergen caused by the release of chemicals stored in...
Mast cells
During inflammation, release of ______________ and other chemicals causes an increase in vascular permeability at the site of injury
Histamine
During inflammation, large numbers of leukocytes pass through blood vessel walls into the injured tissue through...
Chemotaxis
Fibers and ground substance make up the...
ECM; extracellular matrix
The most abundant protein in the body
Collagen
The most abundant type of collagen found in skin, tendons and ligaments
Type I
Type of collagen that resists tension
Type I
Type of collagen found in cartilage
Type II
Type of collagen that resists compression
Type II
Type of collagen found in muscle, blood vessels, and the lymphatic system
Type III
Type of collagen that maintains structural integrity of expandable organs and forms reticular fibers
Type III
Type of collagen found in basal laminae
Type IV
Type of collagen that supports epithelial cells and functions in filtration
Type IV
Fibers formed of type I collagen bundles
Collagen fibers
Name for delicate fibers formed of type III collagen
Reticular fibers
Fibers formed of a protein called elastin
Elastic fibers
A highly hydrated, gel-like substance which fills the space between fibers and cells in connective tissue
Ground substance
The functions of ground substance
Allow diffusion of molecules
Act as a lubricant
Provide barrier to infection
Ground substance is made up of...
GAGs
Proteoglycans
Multiadhesive glycoproteins
GAGs are...
Polysaccharide chains
The most abundant GAG is...
Hyaluronan; hyaluronic acid
Larger molecules within ground substance consisting of a core protein to which varying numbers of GAGs are bonded
Proteoglycans
Component of ground substance that binds cells to their substrate
Multiadhesive glycoproteins
The loose areolar connective tissue forms the ____________ layer
Lamina propria
What type of connective tissue contains cells, fibers and ground substance in roughly equal amounts?
Losse connective tissue; areolar connective tissue
This tissue can resist stress in any direction
Dense Irregular Connective Tissue
This tissue is found in the dermis of the skin, in deep fascia, and the capsule of organs such as the kidney or spleen
Dense Irregular Connective Tissue
This tissue can resist stress in one direction
Dense Regular Connective Tissue
This tissue is found in tendons, aponeuroses and ligaments
Dense Regular Connective Tissue
This tissue functions as a filter, removing worn out red blood cells in the spleen and pathogens in the lymph nodes
Reticular tissue
Tissue repair involved the activity of what cells?
Fibroblasts
______________ are fibroblasts which behave like smooth muscle
Myofibroblasts
This is the most accurate method of determining body composition.
Hydrostatic weighing
T/F: The epithelial membranes are composed of only epithelial tissue
False
1 multiple choice option