Nucleophiles, Bases, Solvents

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Chemistry

Organic Chemistry

Last updated 11:32 PM on 12/12/24
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40 Terms

1
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I-

Nucleophile only

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Br-

Nucleophile only

3
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Cl-

Nucleophile only

4
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H-S-

Nucleophile only

5
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R-S-

Nucleophile only

6
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:N=C:-

Nucleophile only

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N-=N+=N-

Nucleophile only

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H2S

Nucleophile only

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R-S-H

Nucleophile only

10
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<p>tBuO<sup>-</sup></p>

tBuO-

Base only (large)

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<p>LDA</p>

LDA

Base only (large)

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<p>tBu-Li</p>

tBu-Li

Base only (large)

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Na+H-

Base only

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K+H-

Base only

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H-O-

Strong Nucleophile and Base

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Me-O-

Strong Nucleophile and Base

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Et-O-

Strong Nucleophile and Base

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R-O-

Strong Nucleophile and Base

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<p>Carboxylate</p>

Carboxylate

Stronger Nucleophile than base

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<p>Phenoxide</p>

Phenoxide

Stronger Nucleophile than base

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H2O

Weak Nucleophile and Base

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MeHO

Weak Nucleophile and Base

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EtHO

Weak Nucleophile and Base

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RHO

Weak Nucleophile and Base

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H2O (solvent)

polar protic solvent

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EtHO (solvent)

polar protic solvent

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MeHO (solvent)

polar protic solvent

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RHO (solvent)

polar protic solvent

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tBuO-H

polar protic solvent

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:NH3

polar protic solvent

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Carboxylic acid

polar protic solvent

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<p>DMSO</p>

DMSO

Polar Aprotic solvent

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<p>DMF</p>

DMF

Polar Aprotic solvent

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<p>Acetone</p>

Acetone

Polar Aprotic solvent

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<p>THF</p>

THF

Polar Aprotic solvent

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Ether

Polar Aprotic solvent

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<p>Acetonitrile</p>

Acetonitrile

Polar Aprotic solvent

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Benzene

Nonpolar Aprotic solvent

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<p>toluene</p>

toluene

Nonpolar Aprotic solvent

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Hexane

Nonpolar Aprotic solvent