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Comprehensive vocabulary flashcards covering the etiology, pathophysiology, clinical stages, complications, and nursing management of measles based on the HDNR21205 lecture.
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Measles (Rubeola)
An acute, highly contagious viral infection characterized by fever, cough, runny nose, conjunctivitis, and a generalized maculopapular rash.
Causative Agent
Measles virus, genus Morbillivirus, which is an RNA virus that primarily infects the respiratory tract.
Airborne Transmission
The virus can remain suspended in the air and infectious for up to two hours after an infected person has left the area.
Contagious Period
Starts four days before the rash appears until four days after the rash erupts.
Secondary Attack Rate
Up to 90% of susceptible people exposed to the measles virus will become infected.
Pathophysiology (Initial Infection)
Virus enters the respiratory tract, replicates locally, then spreads to the lymphatic system and bloodstream.
Prodromal Stage
Lasts 2−4 days, characterized by fever up to 105∘F (40.5∘C) and the classic "3 C's": Cough, Coryza, and Conjunctivitis.
Coryza
Runny nose; one of the three classic symptoms (3 C's) observed during the prodromal stage of measles.
Enanthem Stage
Occurs 1−2 days before the rash, marked by the appearance of Koplik spots.
Koplik spots
The pathognomonic sign of measles; small, irregular, bright red spots with a minute bluish-white center found on the buccal mucosa opposite the molars.
Exanthem Stage
Lasts 5−6 days, featuring a non-itchy, red/brown maculopapular rash that blanches when pressed.
Cephalocaudal Spread
The pattern of the measles rash typically starting on the face/behind the ears and spreading from head to toe.
Subacute sclerosing panencephalitis (SSPE)
A rare, late neurological complication of measles infection.
Diagnostic Laboratory Confirmation
Includes Measles-specific IgM antibodies in blood, PCR for viral RNA, or samples from throat swabs, nasopharyngeal swabs, or urine.
Vitamin A Supplementation
WHO-recommended supportive care for measles, such as 200,000IU for children ≥1 year.
Airborne Infection Isolation Room (AIIR)
A negative pressure room where a patient with suspected measles must be placed as part of infection control.
N95 Respirator Mask
Personal protective equipment that nursing staff must wear upon entry to the room of a patient with measles.
Post-Exposure Prophylaxis (PEP)
Unvaccinated contacts may receive the MMR vaccine within 72 hours or Immunoglobulin (IG) within 6 days of exposure to prevent the disease.
MMR Vaccine Schedule
Dose 1 is given at 12 to 15 months of age; Dose 2 is given at 4 to 6 years of age.
Herd Immunity Threshold
High vaccination coverage of 95% is essential to achieve herd immunity and protect those too young or immunocompromised to be vaccinated.