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What is the function of the cell membrane?
Controls movement of substances in and out of the cell
Hydrophilic
Water-loving phospholipid head
Hydrophobic
Water-fearing phospholipid tail
Diffusion
Movement from high concentration to low concentration
Osmosis
Diffusion of water
In osmosis, water moves toward what?
Higher solute concentration
Active transport
Movement from low to high concentration using ATP
What does the sodium potassium pump do?
Pumps 3 Na out and 2 K in
Hypertonic solution effect on cell
Cell shrinks
Hypotonic solution effect on cell
Cell swells
Isotonic solution effect on cell
No net movement of water
Simple squamous epithelium function
Diffusion and filtration
Location of simple squamous epithelium
Alveoli and capillaries
Stratified squamous epithelium function
Protection
Location of stratified squamous epithelium
Skin, mouth, esophagus
Simple cuboidal epithelium function
Secretion and absorption
Location of simple cuboidal epithelium
Kidney tubules and glands
Simple columnar epithelium function
Absorption and secretion
Location of simple columnar epithelium
Digestive tract
Pseudostratified ciliated columnar epithelium function
Moves mucus
Location of pseudostratified epithelium
Respiratory tract
Function of areolar connective tissue
Wraps and cushions organs
Function of adipose tissue
Fat storage and insulation
Dense regular connective tissue location
Tendons and ligaments
Function of hyaline cartilage
Support and reduces friction
Location of fibrocartilage
Intervertebral discs and pubic symphysis
Bone tissue function
Support and mineral storage
Three layers of skin
Epidermis, dermis, hypodermis
Function of epidermis
Protection
Function of dermis
Contains blood vessels, glands, nerves
Hypodermis contains mostly what tissue?
Adipose tissue
Layers of epidermis deep to superficial
Basale, spinosum, granulosum, lucidum, corneum
Function of melanocytes
Produce melanin
Function of keratinocytes
Produce keratin
Function of tactile cells
Touch receptors
Neuron function
Conduct electrical impulses
Neuroglia function
Support and protect neurons
Can neurons reproduce?
No
Can neuroglia undergo mitosis?
Yes
Cell body/soma function
Contains nucleus and organelles
Dendrites function
Receive information
Axon function
Sends action potentials
Axon hillock
Region where action potentials begin
Synaptic knobs function
Release neurotransmitter
Myelin sheath function
Speeds impulse conduction
Nodes of Ranvier
Gaps in myelin sheath
Saltatory conduction
Action potential jumps node to node
Neuron that carries impulses toward CNS
Sensory (afferent) neuron
Neuron that carries impulses away from CNS
Motor (efferent) neuron
Interneuron function
Connects sensory and motor neurons
Ganglion
Collection of neuron cell bodies in PNS
Nucleus
Collection of neuron cell bodies in CNS
Oligodendrocyte function
Forms myelin in CNS
Schwann cell function
Forms myelin in PNS
Astrocyte function
Forms blood-brain barrier and supports neurons
Microglia function
Phagocytosis in nervous tissue
Ependymal cells function
Produce and circulate CSF
Satellite cells function
Support neuron cell bodies in PNS
Normal resting membrane potential of neuron
-70 mV
Threshold potential
Approximately -55 mV
Depolarization
Membrane becomes less negative
What ion enters during depolarization?
Sodium
Repolarization
Membrane returns toward resting potential
What ion leaves during repolarization?
Potassium
Hyperpolarization
Membrane becomes more negative than resting
Absolute refractory period
No new action potential possible
Relative refractory period
Stronger stimulus required for AP
All-or-none law
Action potential either fully occurs or does not occur
What triggers neurotransmitter release?
Calcium entering synaptic knob
EPSP
Excitatory postsynaptic potential
IPSP
Inhibitory postsynaptic potential
Temporal summation
Rapid repeated stimulation by one neuron
Spatial summation
Multiple neurons stimulate simultaneously
Acetylcholine (ACh) function
Stimulates skeletal muscle
Dopamine function
Movement and mood regulation
Serotonin function
Mood regulation
GABA function
Major inhibitory neurotransmitter
Glutamate function
Major excitatory neurotransmitter
Substance P function
Pain transmission
Endorphins function
Reduce pain
Epimysium surrounds
Entire muscle
Perimysium surrounds
Fascicle
Endomysium surrounds
Individual muscle fiber
Sarcolemma
Muscle cell membrane
Sarcoplasm
Cytoplasm of muscle fiber
Function of T tubules
Carry action potentials into muscle fiber
Function of sarcoplasmic reticulum
Stores calcium
Triad
One T tubule and two terminal cisterns
Sarcomere
Functional unit of muscle
Z disc
Boundary of sarcomere
Actin
Thin filament
Myosin
Thick filament
A band
Dark band containing thick filaments
I band
Light band containing thin filaments
H zone
Thick filaments only
M line
Center of sarcomere
Troponin function
Binds calcium
Tropomyosin function
Covers myosin binding sites
Neuromuscular junction
Connection between motor neuron and muscle
Neurotransmitter at NMJ
Acetylcholine