Citric Acid Cycle Study Guide

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Last updated 5:25 AM on 4/15/26
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46 Terms

1
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FAD

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2
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FADH2

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3
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Reactant for Step 0 (Pyruvate)

4
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Product for Step 0, Reactant for Step 1 [Acetyl-CoA (+ CO2)]

5
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Pyruvate dehydrogenase complex (oxidoreductase)

What is the enzyme and class for Step 0?

6
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Oxidative decarboxylation

What reaction is taking place in Step 0?

7
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NAD+/NADH

What redox coenzymes are present in Step 0?

8
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Steps 1, 3, and 4 (+ Step 0)

What steps of the Citric Acid cycle are irreversible?

9
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Reactants for Step 1 (Acetyl-CoA and Oxaloacetate)

10
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Product for Step 1, Reactant for Step 2 (Citrate)

11
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Lyase

What is the class of the enzyme for Step 1 (citrate synthase)?

12
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Claisen Condensation (aldol reaction with thioester)

What reaction is taking place in Step 1?

13
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Intermediate for Step 2 (cis-Aconitate)

14
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Product for Step 2, Reactant for Step 3 (Isocitrate)

15
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Lyase

What is the class of the enzyme for Step 2 (aconitase)?

16
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Dehydration-hydration

What reaction is taking place in Step 2?

17
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Product for Step 3, Reactant for Step 4 [α-Ketoglutarate (+ CO2)]

18
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oxidoreductase

What is the class of the enzyme for Step 3 (isocitrate dehydrogenase)?

19
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Oxidative decarboxylation

What reaction is taking place in Step 3?

20
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NAD+/NADH

What redox coenzymes are present in Step 3?

21
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Product for Step 4, Reactant for Step 5 [Succinyl-CoA (+ CO2)]

22
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Oxidoreductase

What is the class of the enzyme for Step 4 (α-Ketoglutarate dehydrogenase complex)?

23
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Oxidative decarboxylation

What reaction is taking place in Step 4?

24
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NAD+/NADH

What redox coenzymes are present in Step 4?

25
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Product for Step 5, Reactant for Step 6 (Succinate)

26
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Ligase

What is the class of the enzyme for Step 5 (succinyl-CoA synthetase)?

27
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Substrate level phosphorylation

What reaction is taking place in Step 5?

28
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ADP/ATP

What coenzymes are present in Step 5?

29
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Product for Step 6, Reactant for Step 7 (Fumarate)

30
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Oxidoreductase

What is the class of the enzyme for Step 6 (succinate dehydrogenase)?

31
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Dehydrogenation

What reaction is taking place in Step 6?

32
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FAD/FADH2

What redox coenzymes are present in Step 6?

33
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Product for Step 7, Reactant for Step 8 (L-Malate)

34
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Lyase

What is the class of the enzyme for Step 7 (fumarase)?

35
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Hydration

What reaction is taking place in Step 7?

36
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Product for Step 8, Reactant for Step 1 (Oxaloacetate)

37
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Oxidoreductase

What is the class of the enzyme for Step 8 (malate dehydrogenase)?

38
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Dehydrogenation

What reaction is taking place in Step 8?

39
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NAD+/NADH

What redox coenzymes are present in Step 8?

40
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Steps 0 and 4

What steps of the Citric Acid cycle have complexes as enzymes?

41
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Steps 3, 4, and 8

What steps of the Citric Acid cycle release NADH?

42
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Steps 3 and 4 (+ Step 0)

What steps of the Citric Acid cycle release CO2?

43
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Step 6

What step of the Citric Acid cycle releases FADH2?

44
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Step 5

What step of the Citric Acid cycle releases ATP?

45
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Net reaction for Citric Acid Cycle

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46
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Net reaction for Citric Acid Cycle and Glycolysis

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