Gluconeogenesis

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Last updated 6:19 PM on 4/25/26
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8 Terms

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Gluconeogenesis

Synthesis of new glucose from non-carbohydrate precursors

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Main function of gluconeogenesis

to maintain blood glucose levels

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where does gluconeogenesis take place

liver

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bypass enzymes in gluconeogenesis

  • pyruvate carboxylase

  • PEP-carboxykinase

  • fructose 1,6-bisphosphatase

  • glucose-6-phosphatase

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irreversible enzymes in glycolysis

  • hexokiase

  • phosphofructokinase-1

  • pyruvate kinase

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Energy used in gluconeogenesis

4 ATP, 2 GTP, and 2 NADH

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Energy produced in gluconeogenesis

2 NADH

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Hormonal regulation in gluconeogenesis

  • increase in glucagon which glucose is scarce/low blood glucose

  • increase in insulin when glucose is abundant