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The best treatment option for SUDs is meds but…
there is lots of stigma surrounding this in the public
Substance Use Disorder is…
a mental illness
Clinical significant impairment for SUD to be a disorder requires:
2-3 Mild
3-5 Moderate
6 + Severe
Substances release very large amounts of …
dopamine in the nucleus accumbens
many reduce sensitivity of dopamine receptors so you need much more dopamine to get pleasure
SUD Impaired Control
trying to quit but can’t
SUD Social Impairment
getting in the way of functioning
SUD Risky Use
drunk driving, using at work
SUD Pharmacological
more and more use of substances to get high
tolerance gets higher and higher
negative reinforcement to get rid of withdrawal symptoms
There is a year pervalence of ____ for SUDs
17%
25% of those with a SUD have …
another mental illness
Biological Factors for SUD
hereditary (50-60%)
dopamine pathways
age 18-25
substance exposure in utero
Potential epigenetic effects
substance exposure before 18
Psych Factors for SUD
Classical Conditioning
Operant Conditioning
Other mental illnesses
Social factors for SUD
low SES
environmental degridation
media and cultural influences
poor social support and lonliness
drug access
gender (male)
Only 10% of people with a SUD….
are getting the best available treatment that they need
Pharmacological Treatments for SUD
medications
Transcranial magnetic stimulation (TMS) - more severe cases
Psychological Treatments for SUD
motivational interviewing
CBT
12 step program - most effective for alcohol use
Harm Reduction Treatment for SUD
How can we minimize the harm that we can reduce the harm of the addiction
clean needle programs
safe treatment options
narcan
The percentage of those with Schizophrenia who die by suicide is….
5-10%
while 50-90% attempt
Positive symptoms of Schizophrenia
Psychosis
Delusions
Hallucinations
Cognitive symptoms
Inappropriate emotions
Psychosis
a break from reality
Though withdrawal delusions
thoughts are being stolen or controlled
Reference Delusions
I’m the center of things
Persecution Delusions
people are out to get me
Paranoia Delusions
I am being watched
Grandeur Delusions
I am special in some way
Delusions
Beliefs are not grounded in reality
Hallucinations
perceptual experienced are not grounded in sensory reality
Cognitive Symptoms of Schizophrenia
loosening of association - easily loosing train of thought and going all over the place
Negative Symptoms of Schizophrenia
Amotivation
Anhedonia
Alogia
Asociality
Diminished emotional expression
Amotivation
lack of motivation
Anhedonia
lack of interest or pleasure
Alogia
loss of speech or shortening of speech
Asociality
pulling away from connection
Disorganized Symptoms of Schizophrenia
Emotion
Thought
Speech - word salad
Behavior
Psychomotor - freezing
Anosognosia
lack of insight or awareness in what is happening
Phases of onset for Schizophrenia
Premorbid - childhood no symptoms
Predromal - some breif symptoms
Psychotic - full onset of symptoms
Those with Schizophrenia have a …
10-15 year lower life expectancy
80-90% smoke
20 times more likely to be unhoused
Biological Factors for schizophrenia
genes
nuerotransmiter dysregulation
dopamine
glutamate
structural abnormalities in the brain
prenatal birth complications
chronic or early use of marijuana
Social Factors for Schizophrenia
early exposure to abuse or trauma
environment of expressed negative emotion
significant emotional or physical stress
dysfunctional family interactions
Medications for Schizophrenia
First gen - typical antipsychotics
2nd gen - atypical antipsychotics
First generation Meds for Schizophrenia
target dopamine antagonist
affective - clinical significant response 60-70%
Second generation Meds for Schizophrenia
target both dopamine and serotonin
60-70% response rate
Very hard for daily compliance of medicine use for Schizophrenia due to…
anosognosia - don’t think they need the meds to make them better because they don’t think theres anything wrong with them
trying to get the medicine use from daily to monthly
Psychosocial Intervention (in combo w/ meds)
social skills training
independent living skills program
family therapy
employment support
Healthy Trait → …
Extreme Trait → Disorder
Eco-dystonic
separation that your disorder is not part of you, you don’t like it and you want to get rid of it
Personality Disorders are…
Ego-syntonic
Ego-syntonic
thinks that this is you are and you accept it
harder to treat because it is almost like cutting off your own arm
Personality Disorders
persistent patterns of emotions, cognition, and behavior that results in enduring emotional distress for person and/or for others and may cause difficult w/ work or relationships
Personality Disorders have a prevalence of…..
9%
Clusters of Personality Disorders
a. odd or eccentric '
b. dramatic, emotional, or erratic
c. anxious or fearful
Odd or eccentric Cluster types (5.7%)
paranoid
schizoid
schizotypal
Paranoid Personality Disorder
deep mistrust
quick to hold grudges
Schizoid Personality Disorder
detachment from social relationships - no interest in having them
flat affect
Schizotypal Personality Disorder
magical thinking
eccentricity
odd beliefs
Dramatic, emotional, or erratic Cluster type (1.5%)
Antisocial
Borderline
Histronic
Narcissistic
Antisocial Personality Disorder
extreme lack of interest in rights and remorse for other people
criminal behavior
men
Borderline Personality Disorder
women
instability in interpersonal relationships
fear of abandonment
Histrionic Personality Disorder
attention seeking behavior
“making a scene”
Narcissistic Personality Disorder
lack of empathy for others
Anxious or Fearful Cluster (6%)
avoidant
dependent
obsessive compulsive
Avoidant Personality Disorder
avoidant of social interactions
wants to have social interactions but is too scared
Dependent Personality Disorder
can’t do things without others
Obsessive Compulsive Personality Disorder
perfection, sameness, ritual