Top 200 Drugs Section 2: CNS Agents

Neurotransmitters are

chemical messengers

Examples of neurotransmitters

dopamine, norepinephrine, GABA, serotonin, and melatonin

SSRIs

Selective Serotonin Reuptake Inhibitors

Celexa

citalopram

Lexapro

escitalopram

Paxil

paroxetine

Prozac

fluoxetine

Zoloft

sertraline

SSRIs common side effects

nausea, insomnia, loss of appetite, and sexual dysfunction

SNRIs

Seratonin Norepinephrine Reuptake Inhibitors

Cymbalta

duloxetine

Effexor (XR)

venlafaxine (extended release)

Pristiq

desvenlafaxine

SNRIs and SSRIs take

time to take effect

SNRIs side effects

similar to SSRIs

TCAs

Tricyclics

Elavil

amitriptyline

Pamelor

nortriptyline

Tofranil

imipramine

TCAs side effects

drowsiness, dizziness, dry mouth, constipation, sexual dysfunction

Buspar

buspirone

Desyrel

trazodone

Remeron

mirtazapine

Strattera

atomoxetine

Wellbutrin

bupropion

Wellbutrin XL

bupropion, extended release (qd)

Wellbutrin SR

bupropion, sust. release (bid)

Use for buspirone

augments serotonin levels

Use for trazodone

sleep

Use for atomoxetine

norepinephrine reuptake inhibitors

Benzodiazepines

Sedatives

Ativan

lorazepam

Klonopin

clonazepam

Restoril

temazepam

Valium

diazepam

Xanax

alprazolam

Benzodiazepines cause

drowsiness, impaired judgement, respiratory depression, increased risk of fall in elderly

Benzodiazepines is a highly addictive substance, making them

controlled substances

Ambien, Ambien Cr

zolpidem

Lunesta

eszopiclone

Abilify

aripiprazole

Invega

paliperidone

Risperdal

risperidone

Seroquel

quetiapine

Zyprexa

olanzapine

What medications are used for bipolar disorder

antidepressants, antipsychotics, anticonvulsants, and anti-anxiety medications

Depakote

divalproex

Dilantin

phenytoin

Keppra

levetiracetam

Neurontin

gabapentinL

Lamictal

lamotrigine

Tegretol

carbamazepine

Topamax

topiramate

Dilantin and Depakote require

periodic blood tests

Depakote is available as

delayed release and extended releaseP

Adderall, Adderall XR (CII)

dextroamphetamine, amphetamine

Concerta (CII)

methylphenidate, ext. rel.

Focalin (CII)

dexmethylphenidate

Ritalin (CII)

methylphenidate

Vyvanse (CII)

lisdexamfetamine

What is the only non stimulant approved for ADHD treatment

Strattera

Off label treatments for ADHD

clonidine, guanfacine, certain antideppressants

Aricept

donepezil

Namenda

memantine

Antidementia medications

Aricept (early-late stage), Namenda (late stage)

Cogentine

benztropine

Sinemet, Sinemet CR, and Parcopa

carbidopa/levodopa

Amerge

naratriptan

Imitrex

sumatriptan

Maxalt, Maxalt MLT

rizatriptan

Treximet

sumatriptan/naproxen

Zomig, Zomig ZMT

zolmitriptan

Fioricet, Esgic Plus

butalbital/APAP/caffeine

Fiorinal (CIII)

butalbital/ASA/caffeine

Migraine medications

-triptans

When are migraine medications taken

taken at first sight of migraine, could cause serotonin syndromeW

What prevents migraines

beta blockers, tricyclic antidepressants, and anticonvulsants