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4 main macromolecules
carbohydrates, lipids, proteins, nucleic acids
monomers
building blocks of macromolecules or polymers
___ are the monomers of carbohydrates
monosaccharides
___ are the monomers of proteins
amino acids
___ are the monomers of lipids
fatty acids
___ are the monomers of DNA
nucleotides
1st law of thermodynamics
energy can't be created or destroyed, only converted
second law of thermodynamics
every energy transfer or transformation increases the entropy of the universe
entropy
measure of disorder or randomness of a system
enzyme
protein that acts as a biological catalyst and speeds up a chemical reaction
3 ATP producing pathways
glycolysis, citric acid cycle/oxidative phosphorylation, and beta oxidation
glycolysis
the breakdown of glucose/sugar by enzymes in anaerobic conditions, releasing energy and pyruvic acid
ATP
adenosine triphosphate, main source of energy for cells
glucose
C6H12O6
how is energy released from ATP
a phosphate is removed
hydrolysis
the chemical breakdown of a compound due to reaction with water
fermentation
cells release energy in the absence of oxygen, makes alcohol and lactic acid
krebs cycle
second stage of cellular respiration, in which pyruvic acid is broken down into carbon dioxide in a series of energy-extracting reactions in mitochondria
electron transport chain
series of electron carrier proteins that shuttle high-energy electrons during ATP-generating reactions
ATP synthase
enzyme that catalyzes the reaction that adds a high-energy phosphate group to ADP to form ATP
where does photosynthesis occur
chloroplasts in plant cells
where does cellular respiration occur
mitochondria and cytoplasm
transcription
DNA is converted to RNA
translation
mRNA decoded to assemble polypeptides and a protein is produced
four types of post translational modification
phosphorylation, acetylation, hydroxylation, and methylation
phosphorylation
the addition of a phosphate group to a molecule
acetylation
addition of acetyl group
hydroxylation
addition of a hydroxyl group
methylation
addition of a methyl group
proteolysis
breakdown proteins
3 sites of major protein sorting
golgi complex, plasma membrane, and endosomes
endosome
Vesicle formed when a cell takes up material from the surrounding environment using the process of endocytosis
where are transmembrane proteins inserted
endoplasmic reticulum membrane
transmembrane proteins
span the membrane
cotranslational sorting
the sorting process in which the synthesis of certain eukaryotic proteins begins in the cytosol and then halts temporarily until the ribosome has become bound to the ER membrane
four types of chemical signaling found in cells
paracrine signaling, autocrine signaling, endocrine signaling, and signaling by direct contact
paracrine signaling
signal released from a cell has an effect on neighboring cells
autocrine signaling
cells respond to signaling substances that they themselves secrete (target themselves)
endocrine signaling
secreted molecules diffuse into the bloodstream and trigger responses in target cells anywhere in the body
signaling by direct contact
cell targets a neighboring cell through a gap junction
gap junction
channel between two adjacent cells that allows substances to pass between cells, enabling the cells to communicate
cell
smallest unit of life
3 things all cells have in common
cell membrane, cytoplasm, DNA
eukaryotic cells
have a nucleus and other membrane-bound organelles, more complex
prokaryotic cells
do not have a nucleus or other membrane-bound organelles, unicellular and often bacteria
organelle
specialized structure that performs important cellular functions within a eukaryotic cell
nucleus
control center of the cell that contains genetic material
chromatin
form of DNA found inside nuclear membrane
chromosomes
threadlike structures made of DNA molecules that contain the genes
nucleolus
produces ribosomes
ribosomes
protein synthesis
cytoplasm
jellylike fluid inside the cell in which the organelles are suspended
endoplasmic reticulum
smooth or rough depending on presence of ribosomes, packages
vesicle
small cavity or sac that contains materials in a eukaryotic cell
golgi apparatus
stack of membranes in the cell that modifies, sorts, and packages proteins from the endoplasmic reticulum
vacuoles
stores food, water, wastes, and other materials
lysosomes
cell organelle filled with enzymes needed to break down certain materials in the cell
mitochondria
powerhouse of the cell, produces energy (ATP) for cell
t/f cells that need more energy have more mitochondria
true
cytoskeleton
network of protein filaments within some cells that helps the cell maintain its shape and is involved in many forms of cell movement
microfilaments
Fine, threadlike proteins found in the cell's cytoskeleton
microtubules
hollow rod composed of tubulin proteins that makes up part of the cytoskeleton in all eukaryotic cells and is found in cilia and flagella
autotrophic
organisms that make their own food by using energy to convert inorganic molecules into sugars, likely undergo photosynthesis
chloroplast
organelle found in cells of plants and some other organisms that captures the energy from sunlight and converts it into chemical energy (photosynthesis)
chlorophyll
green pigment in plants that absorbs light energy used to carry out photosynthesis
cell wall
rigid structure that surrounds the cell membrane and provides support to the cell (ONLY found in plants)
cell membrane
thin, flexible barrier around a cell; regulates what enters and leaves the cell
difference between plant and animal cells
plant cells have chloroplasts and cell walls, while animal cells do not
cilia
hairlike projections on the outside of cells that move in a wavelike manner
flagella
long, whip-like filament that helps in cell motility
the only human cell with a flagellum is ___
sperm
selectively permeable membrane
a property of cell membranes that allows some substances to pass through, while others cannot
phospholipids
A molecule that is a constituent of the inner bilayer of biological membranes, having a polar, hydrophilic head and a nonpolar, hydrophobic tail
hydrophilic
water loving
hydrophobic
water hating
phospholipid bilayer
plasma membrane layers composed of phospholipid molecules arranged with polar heads facing the outside and nonpolar tails facing the inside
cholesterol
lipid that forms an essential component of cell membranes
role of proteins in membrane
structural support, transports/channels, receptors, self markers
extracellular space
space outside the cell
cell theory
fundamental concept of biology that states that all living things are composed of cells; that cells are the basic units of structure and function in living things; and that new cells are produced from existing cells
germ theory
the theory that infectious diseases are caused by certain microorganisms known as pathogens or "germs"
3 domains
Bacteria, Archaea, Eukarya
how are bacteria and archae different
archae live in extreme environments while bacteria is everywhere; archae lacks peptidoglycan but some bacteria have it and others don't
where would you find archaea
extreme conditions like hot springs
eubacteria
kingdom of unicellular prokaryotes whose cell walls are made up of peptidoglycan
t/f archae are found to cause NO disease in humans
true
two phases of cell cycle
interphase and mitotic phase
interphase
period of the cell cycle between divisions, cell growth
G1 phase of interphase
cell grows: increase in size and synthesize new proteins and organelles
S phase of interphase
DNA replication
G2 phase of interphase
cell growth, prepares for mitosis checks in division
mitotic phases
prophase, metaphase, anaphase, telophase
cytokinesis
division of the cytoplasm
prophase
chromatin condenses into chromosomes
metaphase
second phase of mitosis, during which the chromosomes line up across the center of the cell
anaphase
the third phase of mitosis, during which the sister chromatids separate and move toward opposite poles
sister chromatids
replicated forms of a chromosome joined together by the centromere and eventually separated during mitosis or meiosis II
telophase
the final phase, in which the chromatids or chromosomes move to opposite ends of the cell and two nuclei are formed along with a nuclear membrane
3 checkpoints in cell cycle
G1, G2, M
DNA replication
the process of making a copy of DNA