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Homeostasis
A tendency to maintain a balanced or constant internal state; the regulation of any aspect of body chemistry, such as blood glucose, around a particular level
Sensor
detects a change in the internal environment
Integrator
compares existing conditions with ideal conditions
Effector
acts to return the system to its optimal state
Negative feedback
A type of regulation that responds to a change in conditions by initiating responses that will counteract the change. Maintains a steady state.
Positive feedback
A type of regulation that responds to a change in conditions by initiating responses that will amplify the change. Takes organism away from a steady state.
vasoconstriction
Reduces blood flow and heat transfer by decreasing the diameter of superficial blood vessels.
vasodilation
A widening of the diameter of a blood vessel, increasing blood flow
Endotherms
Animals (such as birds or mammals) that can regulate their body temperature.

Ectotherms
An animals that warms itself mainly by absorbing heat from its surroundings

Pikilotherm
An organism that does not have constant body temperature
Osmoregulation
regulation of solute concentrations and water balance by a cell or organism
Excretory system
the system that removes waste from your body and controls water balance
Nitrogenous
__________________ waste is excreted through the excretory system
Inferior vena cava
A vein that is the largest vein in the human body and returns blood to the right atrium of the heart from bodily parts below the diaphragm.

Renal artery
blood vessel that carries blood to the kidney (C)

Renal vein
blood vessel that carries blood away from the kidney and toward the heart (D)

Aorta
Largest artery in the body

Urinary Bladder
stores urine

Urethra
tube leading from the urinary bladder to the outside of the body

Kidneys
Filter waste from the blood like urea, water, salt and proteins.

Renal cortex
outer region of the kidney

Renal medulla
inner portion of the kidney

Nephron
functional unit of the kidney

Glomerulus
A ball of capillaries surrounded by Bowman's capsule in the nephron and serving as the site of filtration in the vertebrate kidney.
Bowmans capsule
cup-shaped strucutre of the nephron of a kidney which encloses the glomerulus and which filtration takes place.

Proximal tubule
In the vertebrate kidney, the portion of a nephron immediately downstream from Bowman's capsule that conveys and helps refine filtrate.

Loop of Henle
section of the nephron tubule that conserves water and minimizes the volume of urine

Distal tubule
In the vertebrate kidney, the portion of a nephron that helps refine filtrate and empties it into a collecting duct.

Collecting duct
A segment of the nephron that returns water form the filtrate to the bloodstream.

Renal pelvis
funnel-shaped reservoir that collects the urine and passes it to the ureter

Ureter
tube that carries urine from the kidney to the urinary bladder

Blood vessels
tubelike structures that carry blood throughout the body

Glomerular filtration
The first step in urine formation in which substances in blood pass through the filtration membrane and the filtrate enters the proximal convoluted tubule of the nephron.
Tubular reabsorption
process of reclaiming water and solutes from the tubular fluid and returning them to the blood
Tubular secretion
selectively moves substances from blood to filtrate in renal tubules and collecting ducts
water reabsorption
removes water from the filtrate and returns it to the blood
Endocrine glands
Glands of the endocrine system that release hormones into the bloodstream
Hormones
chemical substances that carry messages through the body in blood
neurons
The nervous system uses _______, while the endocrine system uses hormones.
Stimulus
A change in an organism's surroundings that causes the organism to react
Receptor protein
a protein that binds specific signal molecules, which causes the cell to respond
Hypothalamus
brain region controlling the pituitary gland
Pituitary gland
The endocrine system's most influential gland. Under the influence of the hypothalamus, this gland regulates growth and controls other endocrine glands.
circulatory
Hormones are secreted into the _______________ system
target cells
cells that have receptors for a particular hormone
Reception
The target cell's detection of a signal molecule coming from outside the cell.
Signal transduction
A series of molecular changes that converts a signal on a target cell's surface to a specific response inside the cell.
Response
An action or change in behavior that occurs as a result of a stimulus.
Protein hormones
class of hormones that cannot pass through the cell membrane; less likely to be stored in the body. Composed of chains of amino acids
Steroid hormones
enter the target cells and have a direct effect on the DNA of the nucleus. Composed of cholesterol
Water
Protein hormones are __________ soluble
Hydrophilic
Having an affinity for water.
Hydrophobic
Having an aversion to water; tending to coalesce and form droplets in water.
Lipid
Steroid hormones are _________ soluble
gene expression
process by which a gene produces its product and the product carries out its function
Epinephrine
Neurotransmitter secreted by the adrenal medulla in response to stress. Also known as adrenaline.
pineal gland
secretes melatonin

thyroid gland
produces hormones that regulate metabolism, body heat, and bone growth

parathyroid gland
any one of four endocrine glands situated above or within the thyroid gland
adrenal gland
A pair of endocrine glands that sit just above the kidneys and secrete hormones that help arouse the body in times of stress.
Pancreas
Regulates the level of sugar in the blood
Ovary
Gland that produces the egg cells and hormones in women

Testis
male reproductive organ that produces sperm and hormones

Nontropic hormones
directly stimulate cellular metabolism and other activities
Tropic hormones
hormones that stimulate other glands to release their hormones
anterior pituitary gland
Makes and secretes six different hormones: FSH, LH, ACTH, TSH, prolactin, and growth hormone. Controlled by releasing and inhibiting factors from the hypothalamus
posterior pituitary gland
Stores and releases two important hormones, ADH and oxytocin, into the bloodstream.
ADH
antidiuretic hormone
oxytocin
A hormone released by the posterior pituitary that stimulates uterine contractions during childbirth and milk ejection during breastfeeding.
Insulin
A protein hormone synthesized in the pancreas that regulates blood sugar levels by facilitating the uptake of glucose into tissues
Glucagon
A protein hormone secreted by pancreatic endocrine cells that raises blood glucose levels; an antagonistic hormone to insulin.
diabetes mellitus
a group of metabolic disorders characterized by hyperglycemia resulting from defects in insulin secretion, insulin action, or both
Islets of langerhans
cell clusters in the pancreas that form the endocrine part of that organ
Alpha
_________ cells secrete glucagon
Beta
______ cells secrete insulin
Homeostasis
A tendency to maintain a balanced or constant internal state; the regulation of any aspect of body chemistry, such as blood glucose, around a particular level
Type I Diabetes Mellitus
destroys pancreatic beta cells that produce insulin (insulin-dependent)
Type II Diabetes Mellitus
pancreas produces normal to high levels of insulin but cells fail to respond; tends to develop later in life (non-insulin dependent)
Hormone cascade pathway
A hormone can stimulate the release of a series of other hormones, the last of which activates a nonendocrine target cell
Hypothyroidism
condition of hyposecretion of the thyroid gland causing low thyroid levels in the blood that result in sluggishness, slow pulse, and often obesity
Hyperthyroidism
excessive activity of the thyroid gland. Consequently, they feel warm, do not tend to gain weight, sweat profusely, and are sometimes irritable
Calcitonin
Lowers blood calcium levels
Parathyroid hormone
increases blood calcium levels
central nervous system
consists of the brain and spinal cord

peripheral nervous system
the sensory and motor neurons that connect the central nervous system to the rest of the body

Reflex arc
A relatively direct connection between a sensory neuron and a motor neuron that allows an extremely rapid response to a stimulus, often without conscious brain involvement.

Neuron
a nerve cell; the basic building block of the nervous system
Glial cells
cells in the nervous system that support, nourish, and protect neurons
Dendrite
the bushy, branching extensions of a neuron that receive messages and conduct impulses toward the cell body

Cell body
Largest part of a typical neuron; contains the nucleus and much of the cytoplasm

Axon
the extension of a neuron, ending in branching terminal fibers, through which messages pass to other neurons or to muscles or glands
Axon terminal
The endpoint of a neuron where neurotransmitters are stored
Afferent neurons
Nerve cells that carry impulses towards the central nervous system
Interneurons
neurons within the brain and spinal cord that communicate internally and intervene between the sensory inputs and motor outputs
Efferent neurons
Nerve cells that conduct impulses away from the central nervous system
Schwann cells
Supporting cells of the peripheral nervous system responsible for the formation of myelin.
Myelin
A layer of fatty tissue segmentally encasing the fibers of many neurons; enables vastly greater transmission speed of neural impulses as the impulse hops from one node to the next.
membrane potential
The voltage across a cell's plasma membrane.
nerve impulse
A signal transmitted along a nerve fiber.