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Chinchilla is used in auditory research, the anatomical structure of Semipatulous Eustachian tube and accessibility to ear serves as good model for ______
Otitis Media Model
Haemophilus influenzae strain 1128
DPOAE: Distortion product otoacoustic emissions
Pairs of tones tones enter the outer, middle, and inner ear, recording microphones pick up the small sounds coming back from the inner ear, computer averages and processes the responses
Amplitude is greatly reduced or absent with OHC loss

ABR: auditory brainstem response
The neural activity that is transmitted from the inner ear to the auditory brainstem and used to measure the threshold of hearing to acoustic stimulation
Recorded via electrodes on the scalp.

What cage bottom is recommended? if perforations, what size of the hole?
Solid-bottom preferred
Perforations no larger than ½" x ½"
What is the recommended floor size and cage height?
No published floor space or height requirement
1-2ft2 per animal, 12” high
What kind of bedding should be avoided in housing Chinchilla?
Avoid wood products with aromatic hydrocarbons
Paper-based products; Pets- fleece
Dust bath is required in Chinchilla husbandry. How often should it be offered? what happens if it is overused?
15 min, several times per week, avoid overuse
Overuse 🡪 eye irritation, dry skin
Prevent fur from becoming matted, greasy
Avoid for peripartum females
Mastitis
Uterine infection
What is the housing temperature requirement for Chinchilla?
63-77ºF
Prone to heat stress (can die >90ºF)
Ok at 32ºF or less if cold adapted
40-60% humidity
What is the light cycle requirement?
12:12 or 14:10 LD cycle
What should be taken into caution when restraining Chinchilla?
no scruffing
What vessels can be used to collect blood?
Jugular vein
Saphenous vein
What is the life span of Chinchilla?
9-18 years
Chinchilla has Palatal ostium, Who else has a palatal ostium?
Guinea Pigs
2 multiple choice options
HEART MURMURS is _________in Chinchilla, Usually benign
common
What dietary requirement for Chinchilla?
Herbivorous, monogastric hindgut
16-20% protein
2.5-5.5% fat
15-23% fiber
Pelleted diet + FC grass hay
Long pellets 🡪 sit upright and hold pellets to eat
Supplement with small amounts of well-washed leafy greens
What is the temperament of male versus female Chinchilla?
Females may become aggressive in heat or post-partum
Intact males may fight
What can be used to sex Chinchilla?
Anogenital distance
What are the signs for estrus in Chinchilla? How long is the estrus?
Estrus (12-48h) characterized by opened vaginal membrane, reddening, discharge
Wax-like vaginal plug expressed at onset on estrus
Vaginal cytology can determine stage of estrus with 70% accuracy
What kind of breeders are Chinchilla?
seasonally polyestrus; Spontaneous ovulators
How long is the gestation period?
105-120 days
3 multiple choice options
Do Chinchillas have post-partum estrus? duration?
Post-partum estrus 12 h after (lasts 2 d)
How long until kit's eyes open? wean age?
Open in 24 h (newborns fully furred, walk within 1 hour)
Litter size 2-3
Wean around 6 weeks
breeding life up to 10 years
What toxin does CLOSTRIDIUM PERFRINGENS toxins produce?
Gamma, beta, epsilon, iota
What clinical signs are associated with CLOSTRIDIUM PERFRINGENS?
Enterotoxemia and necrotizing hemorrhagic enteritis
Pulmonary edema
Diarrhea
Abdominal pain
Lethargy
Rectal prolapse
Sudden death
What clinical signs are associated with PSEUDOMONAS AERUGINOSA?
Problematic for immunodeficient animals
1/3 of animals are subclinical carriers
Anorexia, weight loss
Diarrhea
Pneumonia
Conjunctivitis with corneal ulceration
Inguinal/genital pustules
Otitis with neurological signs
Facial paralysis
If severe- septicemia and sudden death
What methods can be use to control PSEUDOMONAS AERUGINOSA?
Water quality: Acidificaiton, RO, chlorine treatment, autoclaving, filtering
What clinical signs are associated with YERSINIA SPP.? Zoonotic
Large Intestine mucosal hemorrhage and ulceration
Anorexia, weight loss, enlarged mesenteric lymph nodes
Lethargy
Excessive salivation
Diarrhea +/- bloody
Sporadic deaths
What clinical signs are associated with SALMONELLA SPP.? Zoonotic
Gastroenteritis +/- septicemia
Anorexia, weight loss, lethargy
Diarrhea +/- blood
Tremors, local paralysis
Mucopurulent/hemorrhagic vaginal secretions
Abortion
Sudden death
Has not been reported in laboratory chinchillas*
What clinical signs are associated with LISTERIA SPP.? Zoonotic
Septicemia > encephalitic or reproductive forms
Anorexia, weight loss, lethargy
Abdominal distention
Diarrhea or ↓ fecal production
Rectal prolapse
Torticollis, ataxia
Abortion
Sudden death
What pathology lesions are associated with LISTERIA SPP.?
Pinpoint white-yellow foci in liver, spleen, cecum, intestines, mesentery, lymph nodes, kidney, brain, adrenal glands, myocardium
Hemorrhagic enteritis, impaction
Pleuritis, interstitial pneumonia
Mucometra, necrohemorrhagic metritis
Fetus liver with miliary necrotic foci
How is LISTERIA SPP. transmitted?
Found in environment, contaminated hay or feed
Subclinical carriers
What clinical signs are associated with E. COLI?
Enteric infection 🡪 septicemia 🡪 DIC
Lethargy
Tachypnea
Diarrhea
Death
What clinical signs are associated with Herpes simplex virus 1? (Simplexvirus)
Neurotropic, lifelong infections
Progressive neurologic disease
**Rare - only 2 spontaneous cases reported!**
Reverse zoonosis
Ocular infection as route of entry
Disorientation
Seizures
Atonic lateral recumbency
Conjunctivitis, uveitis
Purulent rhinitis
Sudden death
What clinical signs are associated with LCMV? Zoonotic
subclinical
What clinical signs are associated with Giardia duodenalis? zoonotic
Subclinical 🡪 anorexia and diarrhea, poor coat
shed in feces of healthy animals
What clinical signs are associated with Baylisascaris procyonis?
Cerebral nematodiasis
Ataxia, torticollis, paralysis, stumbling
How is Baylisascaris procyonis transmitted?
Hay contaminated with raccoon feces
Which dermatophyte spp. is the most common in Chinchilla? Zoonotic
Trichophyton mentagrophytes
2 multiple choice options
What stain can be used to detect dermatophytes?
Periodic acid Schiff (PAS) or methenamine silver stain
Wood’s light for M. canis
What clinical signs are associated with HISTOPLASMA CAPSULATUM?
anorexia, weight loss, tachypnea, death within 2-4 d
What pathology lesions are associated with HISTOPLASMA CAPSULATUM?
emphysematous lung with focal hemorrhage and bronchopneumonia, white splenic and liver nodules, glomerular nephritis
What are the causes to Bloat in Chinchilla?
Immature hay or hay rich in clover
Sudden food changes (esp. fresh greens and fruits)
GI inflammation
Lactating females that overeat
Decompress stomach with gastric tube or trocar
Constipation is more common than diarrhea in Chinchilla. What are some of the causes?
Reduced roughage/fiber diet
Obesity, intestinal obstruction/compression
Which bone is the common site for fracture?
Usually tibia (cage bars)
What can be used to treat uterine inertia in Chinchilla?
Uterine inertia
0.5-1 IU/kg of oxytocin + 25-50 mg/kg calcium gluconate
Consider caesarian section after 4 h
Which bacterial agent is associated with conjunctivitis in Chinchilla?
Pseudomonas infection
What antibiotics should be avoided in Chinchilla? Antibiotic-associated dysbiosis & gastroenteritis
penicillins, lincomycin, ampicillin, cephalosporins, erythromycin