IPS1: Dispensing - Part 8 - Drug-Herb Interaction

Proverbs 16:3

exacerbate hypokalemia

[Dug Herb Interaction]

• Liquorice + Diuretic exacerbate ____?

precipitate digoxin toxicity

[Dug Herb Interaction]

• Liquorice (Glycyrrhizin glabra ) + Digoxin precipitate ____ toxicity

falsely elevated digoxin levels

[Dug Herb Interaction]

• Chinese ginseng (Panax ginseng) + Digoxin assay

• Chan Su (bufalin) + Digoxin assay

• Danshen + Digoxin assay

  falsely elevated ____ ?

falsely elevated digoxin levels

[Dug Herb Interaction]

• Chinese ginseng (Panax ginseng) + Digoxin assay = ___?

falsely elevated digoxin levels

[Dug Herb Interaction]

• Chan Su (bufalin) + Digoxin assay

falsely elevated digoxin levels

[Dug Herb Interaction]

• Danshen + Digoxin assay = ____ ?

increases bleeding (anticoagulant effect)

[Dug Herb Interaction]

• Alfalfa (Medicago sativa) + Warfarin

• Angelica (Angelica archangelica) + Warfarin

• Dong Quai (Angelica polymorpha, A. dahurica, A. atropurpurea) + Warfarin

• Chamomile + Warfarin

• Horse chestnut + Warfarin

• Red clover (Trifolium pratense) + Warfarin

  increases ___ effect

increases bleeding (anticoagulant effect)

[Dug Herb Interaction]

• Alfalfa (Medicago sativa) + Warfarin

increases bleeding (anticoagulant effect)

[Dug Herb Interaction]

• Angelica (Angelica archangelica) + Warfarin

increases bleeding (anticoagulant effect)

[Dug Herb Interaction]

• Dong Quai (Angelica polymorpha, A. dahurica, A. atropurpurea) + Warfarin

increases bleeding (anticoagulant effect)

[Dug Herb Interaction]

• Chamomile + Warfarin

increases bleeding (anticoagulant effect)

[Dug Herb Interaction]

• Horse chestnut + Warfarin

increases bleeding (anticoagulant effect)

[Dug Herb Interaction]

• Red clover (Trifolium pratense) + Warfarin

hypoglycemia

[Dug Herb Interaction]

• Asian ginseng (Panax ginseng) + Antidiabetics = ____ ?

hypotension

[Dug Herb Interaction]

• Hawthorn + Antihypertensives = ____ ?

lowering of seizure threshold

[Dug Herb Interaction]

Evening primrose oil + Antiepileptic

Shankapushpi + Antiepileptics

will lead to lowering ____ ?

lowering of seizure threshold

[Dug Herb Interaction]

• Evening primrose oil + Antiepileptic

lowering of seizure threshold

[Dug Herb Interaction]

• Shankapushpi + Antiepileptics

increase bleeding risk

• Borage (Borago officinalis) + Antiplatelet/Anticoagulant drugs

• Bromelain (Ananas comosus) + Antiplatelet/Anticoagulant drugs

• Capsicum + Antiplatelet/Anticoagulant drugs

• Feverfew + Antiplatelet/Anticoagulant drugs

• Garlic + Antiplatelet/Anticoagulant drugs

• Ginkgo (Ginkgo biloba) + Antiplatelet/Anticoagulant drugs

• Turmeric + Antiplatelet/Anticoagulant drugs

  increases ____ risk

increase bleeding risk

[Dug Herb Interaction]

• Borage (Borago officinalis) + Antiplatelet/Anticoagulant drugs

increase bleeding risk

[Dug Herb Interaction]

• Capsicum + Antiplatelet/Anticoagulant drugs

increase bleeding risk

[Dug Herb Interaction]

• Feverfew + Antiplatelet/Anticoagulant drugs

increase bleeding risk

[Dug Herb Interaction]

• Garlic + Antiplatelet/Anticoagulant drugs

increase bleeding risk

[Dug Herb Interaction]

• Ginkgo (Ginkgo biloba) + Antiplatelet/Anticoagulant drugs

increase bleeding risk

[Dug Herb Interaction]

• Turmeric + Antiplatelet/Anticoagulant drugs

increase bleeding risk

[Dug Herb Interaction]

↓ aluminum absorption

[Drug–Drug Interactions] Aluminum-containing antacids + Ascorbic acid

↓ aspirin blood concentration

[Drug–Drug Interactions] Aspirin + Products with aluminum/calcium/magnesium

↓ iron absorption

[Drug–Drug Interactions] Iron + Products with aluminum/calcium/magnesium

↓ vitamin absorption

[Drug–Drug Interactions] Mineral oil + Fat-soluble vitamins

↓ metformin absorption

[Drug–Drug Interactions] Psyllium + Antidiabetic agents (metformin)

delayed absorption of acetaminophen

[Drug–Food/Beverage Interactions] Acetaminophen + Garlic

↑ risk of bleeding

[Drug–Food/Beverage Interactions] Aspirin + Garlic

↓ calcium absorption

[Drug–Food/Beverage Interactions] Calcium + Oxalic acid foods (spinach, rhubarb) / Phytic acid foods (bran/whole-grain cereal)

↓ zinc absorption

[Drug–Food/Beverage Interactions] Zinc + Caffeine/dairy

↓ uric acid excretion

[Drug–Disease Interactions] Aspirin + Hyperuricemia

↑ intraocular pressure (worsen glaucoma)

[Drug–Disease Interactions]

• Diphenhydramine + Glaucoma

• Phenylephrine + Glaucoma

↑ gastric mucosal barrier damage

[Drug–Disease Interactions]

• Naproxen + Peptic ulcer disease

• Ketoprofen + Peptic ulcer disease

↑ vascular resistance

[Drug–Disease Interactions]

• Phenylamine + Hypertension

• Naproxen + Hypertension

• HCl + Hypertension

• Nicotine + Hypertension

↑ GI blood loss

[Drug–Alcohol Interactions] Aspirin + Alcohol

↑ sedation

[Drug–Alcohol Interactions] Diphenhydramine + Alcohol

↑ hypoglycemia risk

[Drug–Alcohol Interactions] Insulin + Alcohol

flushing, tachycardia

[Drug–Alcohol Interactions] Ketoconazole (topical) + Alcohol

↑ blood pressure

[Drug–Alcohol Interactions] Yohimbine + Alcohol