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the brain
electro chemical computer
neurons, synapes
3 lbs
coconut size
15-20% of oxygen
volume decreasing
epilepsy
incorrect electric activity spreads throughout the brain -> random movements
caused by infection, no oxygen, hit to the head
drug to help epilepsy
clonazepam, dampen neural activity so not over stimulated
corpus callosum
connection between two hemi
split brain
cut corpus collosum in order to confine epilepsy, mostly act normal
experiment 1:
1. blank screen
2. fixation cross
3. KEY x RING for 100ms
4. blank what did SB see?
SB says ring
left hand = key
right had = ring
How does experiment 1 work?
1/10 second display so SB cant look around
lateralization makes it so left brain (speaking)/ right hand is conscious of the word ring and right brain/left hand is conscious of the word key
experiment 2:
1. blank screen
2. fixation cross
3. to the left black or white disk
4. blank what did SB see?
1st attempt 50% chance of getting the right result
2nd attempt 100% chance of the correct result
How does experiment 2 work?
the right hemi is conscious of the correct color
the left hemi isn't so it guesses /lies
right hemi has an outburst and shakes the head yes or no
then the left hemi(speaking) can say the correct word
lateralization
LEFT: speaks, understand language, right hand
RIGHT: understand language, swears , left hand
visual fields
each eye see both visual fields but everything to left is processed in the right hemi and visa versa
normals: key is transfered through corpus collusum
zaidel
contact lens that make it so all info is transfered to the right hemi
left hemisphere
gray matter(neurons), incharge/inhibits, happier, deatiled , stroke? = more sad
right hemisphere
white matter(connections between neurons), holistic connections, sadder, faces reality, stroke?= more often happier
inter manual conflict (alien hand)
"naughty left hand"
split brain or damge to supplementary motor cortex
right hand = business, left hand = sexy dress
confabulation
making up stories that are not true
left hemi isn't really aware so it makes up a BS response to explain behavior
main function of brain
reception of signals (external world/ body, AFFERENT nerves)
reaction (process info EFFERENT )
integration ( complex computation
neurons
cells
basic units of nervous system
transport signals/ compute infor
preform computations
parts of a neuron
cell body, dendrites, axon
cell body
contains nuclues
sums up signals to see if the neuron is going to spike or not
keeps cell alive and functioning
dendrites
receive the signals
computation
send info to the cell body
branches impules
axon
send signal to other neurons through terminal fibers
"electric cabel"
transmits impules to muscles/glands
myelin sheath
myelinated axon = signal 10x faster
back of brain to the front
peripheral nerves (not in brain) = Schwann cells
central neveres (in brain) = GILAl oligodendrocytes
synapse
place where two neurons communicate through chemical neurotransmitters and receptors
EPSP (excitatory post-synaptic potential)
excitatory, more likely to fire
IPSP (inhibatory post-synaptic potential)
inhibitory less likely to fire
synaptic cleft
gap between pre and post synamptic nerve
axon membrane
specalized for spikes (action potential)
5 nm thick
bilipid layer
embedded protiens ( bumps channels recptors enzymes, structural)
axon potential
RESTING: outside = Na+, inside = K+, electric = -70mv
tries to mainatin this homeostatis
action potential
begins at hillock
depolarization -- hits threshold (-55mv)
channels open stucture of proteins allowing Na to rush in K+ pushed out
rapid change of electric potential
spiking neurons
1. dendrites recieve the signal
2. accumulate in the cell body and sum up signals
3. electric signal travels down the axon
depolarization
any movement of electric potential towards zero
hyper polarization
any movement of electric potential away from zero
refractory period
1-2 ms reset after the spike, more difficult for the neurons to fire
how often do neurons fire?
250 spikes per second
*** SPIKES ARE ALL OR NOTHING
how does the mylien sheath help action potential
blocks the wave, inbetween gives boosts to the signal as it goes across the axon
exocytosis
spike in presynaptic causes pre vessels to fuse to pre membrane and dump chemicals to synaptic cleft
synaptic transition
receptors = lock, neurotransmitters = key
right key opens the receptor and ions(calcium) flows through into the dentrite changing the electric potential to see if it can spike
how to get rid of neurotransimtters in the synaptic cleft
reuptake (pulls back into the presynaptic and recycles it )
enzyme decativation(chops us the neurotransmitters and pull pieces back into pre synamptic )
GABA
inhibitory neurotransmitter
"tells you no dont eat the cookie"
gutamate
excitatory neurotransmitter
Nor(ephidamine)
stressed, release adrenaline, heart rate increases, activates sympathetic nervous system
fight or flight
dopamine
"reward" signal, expectation vs reality
too much = schizophrenia
too little = parkinsons
OCD
mental anguish/ painful rituals that put you into an infinte loop
too much dopamine in caudate (basal ganglia)
caudate
in the basal ganglia inner part of the brain
associated with species survival memories, clean, viligance, behavior errors
tourettes syndrome
too much dopamine in putamen
coprolalia (cussing/barking)
tics in arms/legs/face
big social impact
to stop is like holding your breath
putamen
in the basal ganglia (deep inside brain)
storage for mother programs (riding a bike, dancings)
sends to the motor cortex
cocaine
blocks the reuptake of dopamine in order to send bigger than normal signals across the cleft
build up tolerance so in order to try and maintain homeostasis eventually removes the receptors
serotoin
indolamine
too little dopamine
depression, mood
antidepressants= agonist more active seretonin because blocks reuptake
monoamines
cateccholamines - tyrosine
indolamines - tryptophan
psychology
scientific study of behavior and mental processes
neuroimaging
shows us which parts of the brain is active when in a particular mental state
brain damage
tells us about how our brain function and how memory guides behavior
decision making
guided by values/ expectations/personality/ how its framed
innate tendencies
experiences esp as a child influence how our personality is shaped
social behavior
influenced by social setting
diverse methods
how approach situations is significant because everyone is different
amygadala
detects whether a memory is emotionally significant leading to longer lasting memories
fear conditioning
show signal then predator now subject has time to run when they see the signal
actively interpreting the even and remembering vividly
soical function
amusement bond understand memories shaped by telling/retelling
PTSD
remembering too much of an even
types of prospectives
deveolpmental, cognative, neural , social, cultural, evolutionary
cerebral cortex
frontal lobes, parietal lobes, temporal lobes, occipital lobes
frontal lobes
brains exceutive center
plan for future, abstract thinking, control impuls
parietal lobes
topmost
weave togethere sensory info to create sens of spatial layout
temporal lobes
interpret sounds
occipital loves
rear
interpret visual info arriving from eyes
Descartes
behavior in a mechanical form, every action is a direct response to an even in the outside word (person)
efferent nerves
carry messages from the central nervous sytem
affernt nuerons
carry messages into the central nervous system
respond to external energy-> tirggering other neurons
projection nuerons
link central to another area long (afferent or efferent)
interneurons
local connections (short) neither efferent or afferent
gila
provides nourishment for neurons/ control nutrient supply, increase speed of neural communication, brain development
excitation threshold
voltage cap that if larger than -55mv fires
resting potential
voltage difference between inside and outside of neural membrane when the neuron is not firing
propagation
spread of action potential down an axon caused by changes in electrical charge
agonists
drugs that enhance neurotransmitter activity
antagonist
drugs that impede neurotramitter activity
endoctrine system
system of glands that release secreations directly into the blood stream and affect organs
hormones
chem released endoctrine system affect metabolism arousal liver sugar output
single cell recording
monitor neuron activity and find how some cells are motion detectors while others are shape dectectors
multi-cell recording
study how each cell is influencing the others and patterns
brain lesion
damage to the cells
transecting
disrupt the flow of information
nueropsycology
gain insight of brain function by studying brain damage
TMS( transcranial magnetic simulation)
provide magnetic stimulation at surface of the skull to temporarily stimulate or disable target brain region
only structures near surface of the brain
EEG electroencephalogram
record electric activity by placing electrodes on scalp
ERG: event related potential
electrical changes to a specific even use EEG
CT/CAT scan
examine brain structure by taking X-rays
find tumors/ damage
MRI (magnetic reasoning imaging)
doc the effect of strong magnetic pulses on brain tissue
PET: position emission tomography
examine brain FUNCTIONS by observing amount of metabolic activity in different brain regions
amount of radioactivity is distributed
fMRI
measures blood flow and oxygen use with in brain to study FUNCTIONS
bold signal
central nervous system
spinal cord and brain
peripheral nervous system
afferent and efferent nerves that extend from the brain and spinal cord and connect to organs and muscles
somatic nervous system
skeletal movement(efferent) and sensory info (afferent)
autonomic nervous system
glands (efferent) and smooth muscles of internal organs and blood vessels (efferent)
sympathetic branch
mobilizes/excites body for physical extersion
parasypathetic branch
restor body to resting state
brain stem
top of spinal cord medella ( breathe / blood) and pons (attentiveness/timing of sleep)
cerebellum
muscle coordination/ equilibrium