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Metabolism
the combined chemical reactions in cells that use or release energy
Macronutrient
nutrients such as carbohydrates, lipids, or proteins that are needed in large amounts
Carbohydrates
organic compounds held together by chemical bonds used to power cellular processes; consists of CHO in a 1 to 2 to 1 ratio
Monosaccharides
simple sugars that come from honey and fruits that are small enough to be absorbed in the bloodstream
Monosaccharide examples
fructose, galactose, glucose
Disaccharides
double sugars that come from milk sugar, cane sugar, beet sugar, and molasses
Polysaccharides
complex carbohydrates composed of many sugars from plant food and glycogen from meat; starch, cellulose (hemicellulose, pectin, lignin)
Lipids
organic compounds that include fats, oils, phospholipids, and cholesterol that supply energy and build structures such as the cellular membrane
Triglycerides
most common dietary fat that consists of three fatty acids and a glycerol backbone
Cholesterol
lipid that provides structural material for cells and organelles and starts synthesis of sex hormones and hormones produced by adrenal cortex
Lipid sources
found in plant and animal based foods; saturated fats are from meat, eggs, milk, lard, palm oil and coconut oil; unsaturated fats are from seed, nut, and plant oils
What is the healthiest lipid and its source?
monounsaturated fats (have one double bond) such as olive, peanut, and canola oil
Sources of cholesterol
liver, egg yolk, whole milk, butter, cheese, meats (NOT plants)
Lipid use
supply energy, containing twice as much chemical energy as carbohydrates and proteins, form acetyl CoA in beta oxidation to produce energy, fat storage
Thiokinase
group of enzymes that use energy from ATP to activate fatty acids
Ketone bodies
compounds produced from excess acetyl CoA such as acetone, acetoacetic acid, and betahydroxybutyric acid that can be changed back into acetyl CoA or are excreted through lungs and kidneys
Ketoacidosis
accumulation of ketone bodies; commonly occurs in people with diabetes and an imbalance in pH
Linolenic acid
essential fatty acid required to synthesize phospholipids; can be acquired from corn oil, cottonseed oil, and soy oil
Liver
controls the total amount of cholesterol in the body by making cholesterol or making bile to break down the cholesterol
Proteins
macronutrient composed of amino acids that contain nitrogen
Protein use
form new protein molecules such as enzymes, clotting factors, skin/hair keratin, elastin, collagen, plasma proteins to regulate water balance, muscle components actin and myosin, hormones, and antibodies; can also supply energy/make fat
Deamination
breakdown of nitrogenous components of protein that can then be used to form glucose or fat depending on body’s needs
Protein sources
meats seafood, poultry, cheese, nuts, milk, eggs, and cereals; legumes (beans, peas) contain less protein
8 Essential amino acids
TIMLKFWV
2 additional essential amino acids in children
Histidine (H) and arginine (R)
All 20 amino acids
how many amino acids must be present for growth and tissue repair to occur?
Complete proteins
have all essential amino acids ex. Milk, meat, eggs
Incomplete proteins
do not have enough of all essential amino acids ex. Zein in corn, plant proteins; must be combined with other sources to make complete
Nitrogen balance
when the amount of nitrogen taken in equals the amount of nitrogen excreted
Negative nitrogen balance
when nitrogen excreted is greater than nitrogen in diet ex. a person who is starving
Positive nitrogen balance
when more protein is being built into new tissue and less is being used for energy or excreted ex. Pregnant women, growing children, athletes
What types of conditions can affect nitrogen balance?
starvation, child development, pregnancy, and muscle training
10%
percent of a person’s diet that should be protein
60-150 grams
grams of protein most people should consume a day
0.8 grams per kilogram of body weight
how much protein a person should take in grams per kilogram
Extra 30 grams of protein per day
How much protein should a pregnant woman take?
Nutritional edema
condition where a protein deficiency causes a decrease in the level of plasma proteins causing a decrease in colloid osmotic pressure causing fluids to collect in tissue
Carbohydrate deficiency
when this is deficient, metabolic acidosis occurs
Lipid deficiency
when this is deficient, weight loss and skin lesions occur
Protein deficiency
when this is deficient, extreme weight loss, wasting, anemia, and growth retardation occurs
What's a calories
amount of heat required to raise the temperature of a gram of water by 1 degree celsius;
Food calorie
amount of heat required to raise the temperature of a kilogram (1,000 grams) of water by 1 degree celsius aka kilocalore
4.1 calories
amount of calories produced from 1 gram of carbohydrate or protein
9.1 calories
amount of calories produced from 1 gram of fat
Basal metabolic rate (BMR)
the rate at which the body uses energy (metabolizes) in basal conditions (when body is awake and at rest); can be tested using thyroid function; energy used for passive body activities
1 calorie per hour
for each kilogram of body weight is required for BMR of adults but varies with sex, body size, body temp, and levels of endocrine gland activity
Males
Who has a higher metabolic rate? Men or women?
Body mass index
weight in kilograms divided by the height in meters squared; measurement of desirable weight
Underweight
having below a desirable body weight; a BMI between 13-18
Normal weight
desirable weight between 19 and 24
Overweight
exceeding desirable weight by 10 to 20%; a BMI between 25 and 30
Obese
exceeding desirable weight by more than 20%; a BMI over 30; excess adipose tissue
Appetite
drive that compels us to seek food
Arcuate nucleus
part of the hypothalamus that controls appetite
Leptin
hormone secreted by adipocytes, suppresses appetite and increases metabolic rate after eating; inhibits neuropeptide y
Insulin
secreted by the pancreas, stimulates adipocytes to uptake glucose, store fat and produce glycogen
Neuropeptide Y
neurotransmitter secreted by the hypothalamus that enhances appetite
Ghrelin
hormone sacred by the stomach that enhances appetite
Adiponectin
protein hormone synthesized in adipose cells that mediates response to insulin and regulates fatty acid catabolism; also has anti-inflammatory effect may help with weight loss
Vitamins ADEK
Fat soluble vitamins (dissolve in fats), associate with lipids, and are influenced by the same factors that affect lipid absorption; heat resistant
B vitamins and vitamin C
water soluble vitamins that are mostly destroyed in cooking and food processes
B vitamins
are essential for cellular metabolism and help oxidize carbohydrates, lipids, and proteins during cellular respiration; all are usually in the same foods but differ chemically and functionally
Thiamine
Vitamin B1; part of a coenzyme called cocarboxylase that oxidizes carbohydrates, destroyed in heat, found in lean meat, liver, eggs, whole grain cereal, leafy green vegetables, legumes
Riboflavin
Vitamin B2; heat stable, found in meats, dairy products, leafy green vegetable, whole grain cereals
Niacin
Vitamin B3, nicotinic acid; heat stable, found in liver, lean meats, peanut butter, legumes
Pantothenic Acid
Vitamin B5; destroyed by heat, acids, and bases, part of coenzyme A, found in meats, whole grain cereals, legumes, milk, fruit, vegetables
Biotin
Vitamin B7; stable in heat, acid, light, destroyed in oxidation and bases; found in liver, egg yolk, nuts, legumes, mushrooms
Folacin
Vitamin B9, folic acid; found in liver, leafy green vegetable, whole grain cereals, legumes
Cyanocobalamin
Vitamin B12; complex cobalt containing compound stable to heat, inactivated by light, regulated by intrinsic factor, stored in liver; found in liver, meats, milk, cheese, eggs
Ascorbic acid
Vitamin C; can be found in plant foods, citrus, and tomatoes
Excess thiamine (B1) causes
vasodilation, cardiac dysrhythmias
Thiamine (B1) deficiency causes
Beriberi (GI disturbance, mental confusion, paralysis), muscular weakness, enlarged heart
dermatitis, blurred vision
Riboflavin (B2) deficiency causes
Flushing, vasodilation, wheezing, liver problems
Excess Niacin (B3) causes
Niacin (B3) deficiency
causes Pellagra, dermatitis, diarrhea, mental disorders
Pantothenic acid (B5) deficiency
causes loss of appetite, mental depression, muscle spasms
Excess vitamin B6
causes numbness, clumsiness, paralysis
Vitamin B6 deficiency
causes convulsions, vomiting, seborrhea lesions
Biotin (B7) deficiency
causes elevated blood cholesterol, nausea, fatigue, anorexia
Folacin (B9) deficiency
causes megaloblastic anemia
Cyanocobalamin (B12) deficiency
causes Pernicious anemia
Excess Ascorbic acid(Vit. C)
causes exacerbated gout and kidney stone formation
Ascorbic acid deficiency
causes scurvy, lowered resistance to infection, and wounds that heal slowly
Major minerals
Calcium, Phosphorus, Potassium, Sulfur, Chlorine, Magnesium (Ca, P, K, S, Cl, Mg) (Can people keep stealing clothing magazines)
Homeostasis mechanisms of minerals
excretion of minerals matches intake of minerals
Trace elements
copper, iodine, cobalt, zinc, fluorine, selenium, chromium (Cu, I, Co, Zn, F, Se, Cr) (can i comb some zebras for some change) make up less than 0.005% of adult body weight
Use of minerals
partake in muscle contraction, nerve impulse conduction, blood coagulation, pH regulation
Malnutrition
poor nutrition that results from a lack of essential nutrients
Starvation
can stay alive 50 to 70 days without food, body digests itself
Marasmus
form of starvation due to lack of calories and protein
Kwashiorkor
protein starvation
Respiration
how an organism acquires energy; exchange of gases between the atmosphere and body cells; breathing
Upper respiratory tract organs
nose, nasal cavity, sinuses, pharynx, larynx
Lower respiratory tract organs
Bronchial tree, lungs, trachea (BLT)
Pathway of breathing
nose/mouth> pharynx> larynx> trachea> Bronchi> bronchioles> alveoli
Pseudostratified ciliated columnar epithelium
also known as the mucus membrane, type of tissue that lines the nasal cavity, sinuses, and larger respiratory tubes
Pseudostratified ciliated cuboidal epithelium
epithelium in the finer tubes beginning at the respiratory bronchioles, has thinner mucus lining
Simple squamous epithelium
epithelium present in the alveoli that is associated with a dense network of capillaries; has no mucus
Right and left main (primary) bronchi
directly branch food of trachea
Lobar (secondary) bronchi
part of tree that branches from the main bronchus