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MUST KNOW: from naplex book 2025
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hydroxyl / alcohol group

ketone

aldehyde

amide

urea

nitro group

nitrate

carbonate

carbAmate

ether

thioether

carboxyl

phenol

imide

sulfonamide

primary amine

tertiary amine

imine

amidine

which functional groups are ACIDIC?
phenol
imide
carboxyl
sulfonamide
(PICS)
which functional groups are BASIC?
primary amine
imine
tertiary amine
amidine
(PITA)