Inflammatory Bowel Disease

1st IBD Peak is between

15 and 25 years

IBD has a 2nd peak in

6th decade

What initiates the inflammation in IBD?

Antigens

Starts in the ________ & moves toward ________

Rectum

Cecum

Inflammation & ulcerations occur in the ________

Mucosal layer

Areas of inflamed mucosa form __________

Psuedopolyps

Tongue-like projections into the bowel lumen

Psuedopolyps

Pain & Cramping in the descending colon alleviated by?

Defecation

Ulcerations have __________ appearance

“cobblestone”

These may cause bowel obstruction

Strictures

S/S of Chron’s disease?

• Diarrhea/bloody stool

• Weight loss

• Crampy, abdominal pain in LLQ relieved by defecation

• Fever

• Fatigue

IBD Complications of the GI Tract

•Hemorrhage

•Strictures

•Perforation

•Fistulas

•Toxic megacolon

Decrease inflammation, used to achieve remission, and is helpful for acute flare-ups. Short term use only.

Steroids

What steroids can be used with IBD?

• Prednisone

• Methylprednisone

• Betamethasone

Anti-inflammatory medications primarily used to induce and maintain remission in mild-to-moderate ulcerative colitis and occasionally Crohn’s disease.

5-ASA (aminosalicylates)

5-ASA (aminosalicylates) medication name/s?

Sulfasalazine (Azulfidine)

Decreases GI inflammation, Effective in achieving and maintaining remission. Used for Mild to moderately severe attacks

5-ASA (aminosalicylates)

Surgical therapy for chronic ulcerative colitis?

• Total colectomy

• Proctocolectomy

Surgical resection & removal of the colon

• Total colectomy

Surgical removal of the entire colon and rectum.

• Proctocolectomy

Goal of Dietary consult?

Provide adequate nutrition without exacerbating symptoms.