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cell theory
cells are the basic unit of life and have a primary responsibility to contribute to homeostasis
3 main parts of human cells
plasma membrane, cytoplasm, nucleus
integral membrane proteins
embedded in the membrane (ex. channel proteins that selectively allow things to pass)
peripheral membrane proteins
on the outer surface of the lipid bilayer, sometimes attached to the surface of an integral protein
functions of membrane proteins
transport, cell recognition, receptor and ligand, anchors for cell structures, enzymes
types of transport across the plasma membrane
passive (simple, facilitated diffusion, osmosis), active (active transport, endocytosis, exocytosis)
simple transport (diffusion)
molecules move from a higher to lower concentration (ex. oxygen and carbon dioxide easily pass)
facilitated diffusion
use protein channels and transport mechanisms to help large, polar, ionic molecules to pass
osmosis
diffusion of water through a semi-permeable membrane down its concentration gradient
osmolarity
concentration of solutes in a solvent, high osmolarity means high solute and low water
isotonic
same osmolarity inside and outside the cell (no net water movement)
hypertonic
outside of the cell has higher osmolarity (water leaves the cell = shrinking)
hypotonic
outside the cell has lower osmolarity (water enters the cell.= swelling)
vesicular transport
no membrane carriers, needs ATP
endocytosis
bringing molecules into the cell, the pinched off portion becomes an independent vesicle
exocytosis
cell exporting materials using vesicular transport, vesicle membrane becomes part of the cell membrane (how digestive enzymes and hormones are secreted)
membrane potential
K+ can enter and leave, once K+ inside = K+ outside, this is established
cytoplasm
composed of organelles and cytosol
endomembrane system
ER, golgi, vesicles = set of 3 major organelles that form a system inside the cell
endoplasmic reticulum
system of channels continuous with nuclear membrane covering nucleus and composed of lipid bilayer
rough ER
membrane dotted with embedded granules (ribosomes), good for protein synthesis
smooth ER
no ribosomes, synthesis of lipids + phospholipids + steroids, stores and regulates Ca++, metabolizes carbs
golgi apparatus
sorting, modifying, shipping products that come from the rough ER and produces lysosomes
lysosomes
contain digestive enzymes that breakdown several organic compounds
peroxisomes
specialized lysosomes, deal with toxins and located in liver cells
ribosomes
site of protein synthesis, made of 2 ribosomal RNA units around mRNA and followed by protein synthesis
mitochondria
energy transformer of the cell *muscle and neural cells are packed with mitochondria*
cytoskeleton
fibrous protein that provide structural support for cells + critical for mobility, reproduction and transport of substances (made of microfilaments, microtubules, intermediate filaments)