Veterinary Immunology - Module 1: Introduction and History

A comprehensive set of vocabulary flashcards covering the definitions and historical milestones of immunology as presented in Module 1 of VMIC104A.

Immunity

The capability of multicellular organisms to resist harmful microorganisms and the immune system's way of protecting the body against infectious disease.

Edward Jenner

Initiated smallpox vaccination in 1798.

Paul Erlich (1877)

The scientist who recognized mast cells.

Louis Pasteur (1879)

Developed an attenuated chicken cholera vaccine.

Elie Metchnikoff

Developed the cellular theory of vaccination in 1883.

Louis Pasteur (1885)

Developed the rabies vaccine.

Robert Koch

Explored delayed type hypersensitivity in 1891.

Paul Erlich (1900)

Theorized specific antibody formation.

Clemens von Pirquet

Coined the word allergy in 1906.

John Marrack

Formulated the antigen-antibody binding hypothesis in 1938.

Jules Freund and Katherine McDermott

Researchers who explored adjuvants in 1942.

Macfarlane Burnet & Frank Fenner

Formulated the immunological tolerance hypothesis in 1949.

Clonal selection theory

Developed in 1959 by Niels Jerne, David Talmage, and Macfarlane Burnet.

Interferon (cytokine)

Discovered in 1957 by Alick Isaacs and Jean Lindemann.

Rodney Porter and team

Discovered the structure of antibodies in 1962.

Jaques Miller and team

Discovered thymus involvement in cellular immunity in 1962.

Noel Warner and team

Distinguished between cellular and humoral immune responses in 1962.

Anthony Davis and team

Discovered T cell and B cell cooperation in immune response in 1968.

Rolf Zinkernagel and Peter Doherty

Explored major histocompatibility complex restriction in 1974.

Susumu Tonegawa and Leroy Hood

Identified immunoglobulin genes in 1985.

Leroy Hood and team (1987)

Identified genes for the T cell receptor.