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cause of CIN
HPV
high-risk oncogenic HPV causing CIN and cervical K
16,18,31
CIN classification
dysplastic changes up to 1/3 of epithelial thickness
up to 2/3
>2/3, w/o crossing BM
risk factors CIN
early onset sex, lots partners, historey STDs
dg CIN
pap, hpv teest, colpo + bioopsy