purine synthesis
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16 Terms
purine synthesis step 1
phosphoribosylpyrophosphate synthetase
phosphoribosylpyrophosphate synthetase
ribose 5 phosphate to phosphoribosylpyrophosphate
purine synthesis step 2
glutamine phosphoribosylpyrophosphate amidotransferase
glutamine phosphoribosylpyrophosphate amidotransferase
phosphoribosylpyrophosphate to phosphoribosylamine
purine synthesis step 3
11 things
11 things
phosphoribosylamine to inosine monophosphate
amp branch 1
inosine monophosphate and aspartate to adenylosuccinate
amp branch 2
adenylosuccinate to fumarate and adenosine monophosphate
gmp branch 1
inosine monophosphate and nad to xanthosine monophosphate and nadh
gmp branch 2
xanthosine monophosphate and glutamine to guanosine monophosphate
rate limiting step
glutamine phosphoribosylpyrophosphate amidotransferase
1 of 5 to make imp
glycine
2 of 5 to make imp
formyltetrahydrofolate
3 of 5 to make imp
co2
4 of 5 to make imp
aspartate
5 of 5 to make imp
glutamine