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Which hormone increases K+ concentration in the urine?
Aldosterone
The main determinant of intracellular osmolarity and cellular volume is
Potassium
During alkalosis, skeletal muscles have _______ activity
Increased
Dehydration (negative water balance). Osmolarity of bodily fluids will be
Hypertonic
This hormone increases H2O reabsorption without increasing Na+ reabsorption
ADH
Overhydration (water intoxication). Osmolarity of bodily fluids will be
Hypotonic
When BP rises, the hormone _______ rises
Natriuretic peptide
Hypotonic urine occurs with
Hyposecretion of ADH
Which of the following can cause rapid onset of hyperkalemia
Hemolytic disease
Internal or external bleeding creates hypovolemia. Osmolarity of bodily fluids will be
Isotonic
Which of the following cause hypocalcemia
Hypoparathyroidism
Where is Na+ highest
ECF
Which of these is within the normal pH range for blood
7.4
Which of the following is the most important buffer system in the human body
Bicarbonate
Slow, but fully restorative pH adjustments are made by the
Urinary system
Hypoventilation causes
Respiratory acidosis
A chemical that prevents rapid change in pH is called a
buffer
Which of these is outside the normal pH range for urine 8.3
Which of the following causes hypokalemia
Sweating
Which of these is a cause of slow onset hyperkalemia
Renal failure
Where is K+ highest
ICF
Rapid pH adjustments are made by the
Respiratory system
During acidosis, the Hb-O2 curve shifts to the
right
Where is Ca++ highest
ECF
During acidosis of the CSF
Coma is possible
During alkalosis, the Hb-O2 curve shifts to the
left
Which of the following leads to muscle weakness
Hypokalemia
During respiratory compensation for acidosis
Ventilation increases
Which of these approximates obligatory water loss in mL/day
400-500
Which of these approximates obligatory water loss in L/day
0.5
Which of the following causes metabolic alkalosis
Vomiting
Overhydration (hypotonic hydration/water intoxication) may be caused by
ADH hypersecretion
Na+ retention leads to
Hypertension
Which of the following causes metabolic acidosis
Severe diarrhea
The greatest % of body’s water is in the
Intracellular fluid
Which of the following leads to muscle weakness
Hypercalcemia
During renal compensation for acidosis
H+ secretion increases
Which of the following causes hypercalcemia
Hyperparathyroidism
Edema means fluid accumulation in the
Interstitial fluid
Which of these causes respiratory acidosis
Pneumonia
Where is ADH released
Posterior pituitary of hypothalamus
What does ADH do
Increase water reabsorption in kidneys, decreases urine
What does RAAS do
Stimulated when BP drops, causes vasoconstriction, Na+ retention, water retention, and increases BP
Where is Aldosterone released
Adrenal cortex
What does Aldosterone do
Increase Na+ reabsorption, water follows sodium, Increases blood volume
Why is Natriuretic Peptides
Released when BP is too high
What does Natriuretic Peptides do
Increase Na+ excretion, increase urine output, decrease BP
What decreases Calcium
Calcitonin
What increases Calcium
PTH (parathyroid hormone)
Why does Caffeine cause urination
Inhibits Na+ reabsorption and water follows sodium
Why does Alcohol causes urination
Inhibits ADH → less water reabsorbed
What is Hypernatremia
Sodium imbalance caused by IV saline, causes water retention, hypertension, and edema
What is Hyponatremia
Sodium imbalance caused by sweating or only drinking water, causes diluted electrolytes and neurological problems
What is Hyperkalemia
Potassium imbalance
What is rapid hyperkalemia caused by
Crush injury and hemolysis, leads to possible cardiac arrest and excitable cells
What is slow hyperkalemia caused by
Renal failure and low aldosterone, leads to less excitable cells
What is Hypokalemia
Potassium imbalance caused by vomiting, diarrhea, sweating, laxatives, aldosterone excess
What results from Hypokalemia
Hyperpolarization, muscle weakness, arrhythmias
What is hypercalcemia
Calcium imbalance caused by hyperparathyroidism and alkalosis, leads to decreased nerve excitability, muscle weakness, cardiac arrhythmias
What is Hypocalcemia
Calcium imbalance caused by Vitamin D deficiency, pregnancy, and hypoparathyroidism, leads to increased nerve excitability, tetany, and death
What causes metabolic acidosis
lactic acid, keto acids, renal failure, diarrhea
What causes metabolic alkalosis
Vomiting (loss of stomach acid), antacids, alkaline foods
What causes respiratory acidosis
Hypoventilation, CO2 builds up
What causes respiratory alkalosis
Hyperventilation, CO2 decreases
How to compensate for metabolic acidosis
Increase breathing to remove CO2
How to compensate for metabolic alkalosis
Decrease breathing, retain CO2
How do kidneys regulate pH
By controlling H+ secretion and reabsorbing bicarbonate
What is the range for urine pH
4.5-8.2