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Ideal drug
effective, safe, selective
Term to know the drug has a therapeutic effect
effectiveness
Purpose of a blind study in clinical trials
To reduce bias
Teratogenicity
potentially cause harm to fetus
drug selectivity means
has a specific target
6 rights of drug administration
1. Right Patient
2. Right Drug/Med
3. Right Dose
4. Right Route
5. Right Time
6. Right Documentation
*understand what right an issue would be pertaining to (wrong time for instance)
geriatric patients have increased risk for drug effects due to
they metabolize slowly
pediatric patients have increased risk for med errors because..
many doses are weight-based
How to prevent medication errors
Follow 6 rights
1. Right Patient
2. Right Drug/Med
3. Right Dose
4. Right Route
5. Right Time
6. Right Documentation
Understand the pediatric vaccine schedule..
Hepatitis B vaccine is given..
Shortly after birth
Give patient Penicillin, a reaction occurs shortly after given, what to do?
Stop and administer epi (epinephrine)
Important patient teaching point for cephalexin
Patient needs to complete the full course of therapy
Patient receives maropenem....****** double check this question
Seizure activity
If patient receives vancomycin and begins presenting with red skin, what do you do?
Patient is developing red man syndrome (infusion reaction), need to slow the infusion rate to resolve the symptoms.
Instruction for teaching patient taking cifrofloxacin
limit sun exposure
Patient taking sulfamethexilone presents with widespread rash and blistering...what do you do?
Patient has Steven's Johnson Syndrome, need to STOP med. Treat rash/blistering like a burn.
Patient education with doxycycline
Contraindicated in pregnancy and young children
Patient needs further teaching with metronidazole if says..
"It's safe to drink wine"
Patient with herpes, education...
Can cause nephrotoxicity, ensure adequate hydration
Antifungal associated with nephrotoxicity and highly toxic
amphotericin B (aka amphoterrible)
antifungal med class suppresses synthesis and fungal cell membranes
azoles
Which antifungal is used for swish and swallow (or spit)?
Nystatin
What is pharmicokinetics?
what the body does to the drug (Absorption, distribution, metabolism, excretion = ADME)
Which immunosuppressant requires regular eye exams?
hydroxychloroquine
toxicity....trough level monitor.... double check question***
Tochrolymis (used to prevent organ rejection)
Med causes bone marrow suppression
mycophenolate mofetil
What drug requires TB screening first?
Methotrexate (used for RA)
What med class increases acetylcholine?
Cholinesterase inhibitors
Crisis from too much acetylcholinesterase?
Cholinesterase crisis
Crisis from insufficient acetylcholinesterase?
Myasthenia crisis