Therapeutic Drug Levels

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Monitoring Parameters

Last updated 10:52 PM on 5/14/26
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11 Terms

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Carbamazepine

4 - 12 mcg/mL

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Digoxin

0.8 - 2 ng/mL (Afib)

0.5 - 0.9 ng/mL (HF)

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Gentamicin

Peak: 5 - 10 mcg/mL

Trough: < 2 mcg/mL

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Lithium

0.6 - 1.2 mEq/L (up to 1.5 mEq for acute symptoms) as a trough

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Phenytoin/Fosphenytoin

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Free Phenytoin

10 - 20 mcg/mL; if albumin is low, calculate a corrected level

Free Phenytoin: 1 - 2 mcg/mL

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Procainamide

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NAPA (procainamide, active metabolite)

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Combined

4 - 10 mcg/mL

15 - 25 mcg/mL

10 - 30 mcg/mL

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Theophylline

5 - 15 mcg/mL

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Tobramycin

Peak: 5 - 10 mcg/mL

Trough: < 2 mcg/mL

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Valproic Acid

50 - 100 mcg/mL (up to 150 mcg/mL in some patients)

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Vancomycin

Serious Infections

AUC/MIC: 400-600

Trough: 15 - 20 mcg/mL

Other infections:

Trough - 10-15 mcg/mL

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Warfarin

Goal INR: 2-3 for most indications

INR of 2.5 - 3.5 = high-risk conditions such as mechanical mitral valve