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addiction
clinically-impairng pattern of inflexible reward pursuit and consumption; a clinical brain disorder with observable physiological manifestations that underlie pathological aspects of behavior
progression of drug abuse
use → heavy use → early dependence → late dependence/neurodevelopment

what happens in between each stage of the progression of drug abuse?
abstinence and relapse

what does point a on the drug use graph indicate?
first time use - euphoria, feel good, reduces stress (above homeostatic point)
what does point b on the drug use graph indicate?
i need this drug to get by - depression, agitation, anxiety (below homeostatic point)