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digestive system
organ system that processes food, extracts nutrients, and eliminates residue
ingestion
selective intake of food
digestion
mechanical and chemical breakdown of food into a form usable by the body
absorption
uptake of nutrient molecules into the epithelial cells of the digestive tract and then into the blood and lymph
compaction
absorbing water and consolidating the ingestible residue into feces
defecation
elimination of feces
mechanical digestion
the physical breakdown of food into smaller particles; cutting and grinding action of the teeth; churning action of stomach and small intestines; exposes more food surface to digestive enzymes
chemical digestion
a series of hydrolysis reactions that break dietary macromolecules into their monomers; carried out by digestive enzymes produced by salivary glands, stomach, pancreas, and small intestines
digestive tract (alimentary canal)
30 ft long muscular tube extending from mouth to anus; mouth, pharynx, esophagus, stomach, small intestine, and large intestine; gastrointestinal tract (GI) tract is the stomach and intestines
accessory organs
teeth, tongue, salivary glands, liver, gallbladder, and pancreas
mucosa (mucous membrane)
lines the lumen
lamina propria
loose connective tissue
muscularis mucosal
thin layer of smooth muscle
submucosa
thicker layer of loose connective tissue; contians blood vessels, lymphatic vessels, a nerve plexus, and in some places mucus-secreting glands that dump lubricating mucus into the lumen
muscularis externa
consists of usually 2 layers of muscle near the outer surface; responsible for the motility that propels food and residue through the tract
inner circular layer
cells encircle tract
outer longitudinal layer
cells run longitudinally
serosa
composed of a thin layer of areolar tissue topped by simple squamous mesothelium; begins in the lower 3 to 4 cm of the esophagus, ends just before the rectum
enteric plexus
nervous network in esophagus, stomach, and intestines that regulates digestive tract motility, secretion, and blood flow
submucosal plexus
found in submucosa; controls glandular secretions of mucousa, and movements of muscularis mucosae
myenteric plexus
ganglia and nerve fibers between the 2 layers of the muscalaris external; controls peristalsis and other contractions of muscularis externa
mesentery
connective tissue sheet that suspends stomach and intestines from abdominal wall
lesser omentum
a ventral mesentry that extends from the lesser curvature of the stomach to the liver
greater omentum
hangs from the greater curvature of the stomach (its left inferior margin); covers small intestine like an apron
mesocolon
portion of mesentry that anchors transverse colon to posterior abdominal wall
intraperitoneal
when an organ is enclosed by mesentery (serous) on both sides; stomach, liver, and parts of small and large intestine
retroperitoneal
when an organ lies against the posterior body wall and is covered by peritoneum on its anterior side only; considered to be outside the peritoneal cavity; duodenum, pancreas, and parts of the large intestine (ascending colon, descending colon, and rectum)
short (myenteric) reflexes
stretch or chemical stimulation acts through myenteric plexus; stimulates peristaltic contractions of swallowing
long (vasovagal) reflexes
parasympathetic stimulation of digestive motility and secretion
oral fissure
anterior opening between lips
fauces
posterior opening to the throat
labial frenulum
median fold that attaches each lip to the gum between the anterior incisors
vestibule
space between cheeks or lips and the teeth
tongue
muscular, bulky, but agile and sensitive organ; manipulates food between teeth, senses taste and texture food
lungual papillae
bumps and projections that are the sites of most taste buds
vallate papillae
a V-shaped row of papillae that mark the boundary between the body and root of the tongue
terminal sulcus
groove behind the vallate papillae
lingual frenulum
median fold that attaches the body of the tongue to the floor of the mouth
lingual glands
serous and mucus glands within tongue, amid the extrinsic muscles; secrete a portion of the saliva
lingual tonsils
contained in the root
palate
separate oral cavity from nasal cavity
hard (bony) palate
anterior portion that is supported by the palatine processes of the maxillae and the palatine bones
palatine rug
transverse ridges that help the tongue hold and manipulate food
soft palate
posterior to hard palate with more spongy texture
uvula
conical medial projection visible at the rear of the mouth; helps retain food in the mouth until one is ready to swallow
teeth
collectively called the dentition
mandible
lower jaw
maxilla
upper jaw
incisors
chisel-like cutting teeth used to bite off a piece of food
canine
pointed teeth that act to puncture and shred food
premolars
broad surface teeth for crushing, shredding, and grinding
molars
even broader surface teeth for crushing, shredding, and grinding
periodontal ligaments
modified periosteum whose collagen fibers penetrate into the bone on one side and into the tooth on the other; anchors tooth firmly in alveolus; allows slight movement under pressure of chewing
gingiva (gums)
covers the alveolar bone
crown
portion of the tooth above the gum
root
portion of the tooth below the gum, embedded in alveolar bone
neck
point of the tooth where crown, root, and gum meet
gingival sulcus
space between the tooth and the gum
dentin
hard yellowish tissue that makes up most of the tooth
enamel
noncellular secretion that cannot regenerate; covers crown and neck of tooth
cement
covers root
root canal
space in root leading to pulp cavity in the crown; contain nerves and blood vessels
apical foramen
pore at the basal end of each root canal
plaque
sticky residue on teeth made of bacteria, sugars
gingivitis
gum inflammation
peridontal disease
when gingivitis progresses to affect bone
mastication (chewing)
breaks food into smaller pieces to be swallowed and exposes more surface to digestive enzymes
mucus
binds and lubricates a mass of food and aids in swallowing
lysozyme
enzyme that kills bacteria
immunoglobulin A (IgA)
antimicrobial antibody
salivary amylase
enzyme that begins starch digestion on the mouth
lingual lipase
enzyme that begins fat digestion in the mouth (but mainly after the food is swallowed)
intrinsic (minor) salivary glands
small glands dispersed amid other oral tissues; secrete saliva at constant rate (whether we are eating or not)
extrinsic (major) slaivary glands
three pairs of larger, more discrete organs connected to oral cavity by ducts
parotid glands
located beneath the skin anterior to the earlobe; parotid duct passes over master, peirces buccinator, and opens into mouth
submandibular gland
lacated halfway along the body of the mandible; duct empties at the side of the lingual frenulum, near the lower central incisors
sublingual gland
located in the floor of the mouth; has multiple ducts that empty posterior to the papilla of the submandibular duct
pharynx
muscular funnel connecting oral cavity to esophagus and nasal cavity to larynx
esophagus
straight muscular tube 25 to 30 cm long between pharynx and stomach
heartburn
burning sensation produced by acid reflux into the esophagus
swallowing or deglutition
a complex action involving over 22 muscles in the mouth, pharynx, and esophagus
oral phase of swallowing
under voluntary control; tongue collects food, presses it against palate forming bolus, and pushes it posteriorly; food accumulates in oropharynx in front of epiglottis; epiglottis tips posteriorly and food bolus slides around it and into laryngopharynx
pharyngeal pahse of swallowing
involuntary; prevents food and drink from reentering mouth or entering the nasal cavity; breathing is suspended; infrahyoid muscles pull larynx up to meet epiglottis and cover laryngeal opening; vocal cords adduct to close airway; upper esophagus widens; food bolus is driven downward of constriction of the upper, then middle, and finally the lower pharyngela constrictors
esophageal pahse of swallowing
waves of involuntary contractions called peristalsis; peristalsis coordinated by both swallowing center and myenteric pplexus in esophageal wall; circular muscle constricts above bolus, relaxes below bolus; when standing or sitting upright, food and liquid drops through esophagus by gravity faster than peristalsis can keep up with itl peristalsis ensures you can swallow regardless of body position; liquid reaches the stomach in 1 to 2 seconds; food bolus in 4 to 8 seconds; when it reaches lower end of the esophagus, the lower esophageal sphincter relaxes to let food pass into the stomach
stomach
a muscular sac in upper left abdominal cavity immediately inferior to the diaphragm; primarily functions as a food storage organ
cyme
acidic, soupy mixture of semidigested food that passes on to the small intestine
cardiac part
small area within about 3 cm of the cardiac orifice
fundic region (fundus)
dome superior to the esophageal attachment
body
makes up the greatest part distal to cardiac orifice
pyloric part
narrower pouch at the inferior end
pylorus
narrow passage to duodenum
pyloric sphincter
ring of smooth muscle around pylorus; regulates the passage of chyme into the duodenum
gastric pits
depressions in gastric mucosa, lined with the same columnar epithelium as the surface
mucous cells
predominate in cardiac and pyloric glands; secrete mucus
regenerative (stem) cells
found in the base of pit and in neck of gland; divide rapidly and produce continual supply of new cells to replace cells that die
parietal cells
found mostly in the upper half of the gland; secrete hypochloric acid (HCl), intrinsic factor, and a hunger hormone called ghrelin
chief cells
most numerous cell type; secrete gastric lipase and pepsinogen; dominate lower half of gastric glands; absent from pyloric and cardiac glands
eteroendotocrine cells
concentrated in lower end of a gland: secrete hormones and paracrine messengers that regulate digestion; at least eight kinds of these cells, each which produces a different chemical messenger
gastric juice
2 to 3 L per day produced by the gastric glands; mainly a mixture of water, hydrochloric acid, and pepsin
zymogens
digestive enzymes secreted as inactive proteins; converted to active enzymes by removing some of their amino acids