DNA

Electrostatic action

Electrostatic action

________ between the positive charge histone and the negative phosphates of the DNA are an important stabilizing force in maintaining chromatin structure.

Heterochromatin

________: highly condensed in comparison to euchromatin.

Euchromatin

________: DNA that is undergoing normal packing.

Radial loop domains

________: interaction between 30- nanometer fibers and nuclear matrix.

Major groove

________: proteins bind to affect gene expression.

Major groove

proteins bind to affect gene expression

Minor groove

narrower

2nd level coiling of the beads into a helical array

30nm fiber = chromatin

Radial loop domains

interaction between 30-nanometer fibers and nuclear matrix

Euchromatin

DNA that is undergoing normal packing

Heterochromatin

highly condensed in comparison to euchromatin

Features of DNA

Double stranded

Antiparallel strands

Right-handed helix

Sugar-phosphate backbone

Bases on the inside

Stabilize H-bonding

Specific base pairing

About 10 nucleotides per helical turn

Chargoff's rules

A pairs with T

G pairs with C

Keeps width consistent