DNA

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13 Terms

1

Electrostatic action

________ between the positive charge histone and the negative phosphates of the DNA are an important stabilizing force in maintaining chromatin structure.

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2

Heterochromatin

________: highly condensed in comparison to euchromatin.

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3

Euchromatin

________: DNA that is undergoing normal packing.

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4

Radial loop domains

________: interaction between 30- nanometer fibers and nuclear matrix.

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5

Major groove

________: proteins bind to affect gene expression.

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6

Major groove

proteins bind to affect gene expression

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7

Minor groove

narrower

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8

2nd level coiling of the beads into a helical array

30nm fiber = chromatin

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9

Radial loop domains

interaction between 30-nanometer fibers and nuclear matrix

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10

Euchromatin

DNA that is undergoing normal packing

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11

Heterochromatin

highly condensed in comparison to euchromatin

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12

Features of DNA

Double stranded

Antiparallel strands

Right-handed helix

Sugar-phosphate backbone

Bases on the inside

Stabilize H-bonding

Specific base pairing

About 10 nucleotides per helical turn

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13

Chargoff's rules

A pairs with T

G pairs with C

Keeps width consistent

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