DNA

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13 Terms

1
Electrostatic action
________ between the positive charge histone and the negative phosphates of the DNA are an important stabilizing force in maintaining chromatin structure.
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2
Heterochromatin
________: highly condensed in comparison to euchromatin.
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3
Euchromatin
________: DNA that is undergoing normal packing.
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4
Radial loop domains
________: interaction between 30- nanometer fibers and nuclear matrix.
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5
Major groove
________: proteins bind to affect gene expression.
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6
Major groove
proteins bind to affect gene expression
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7
Minor groove
narrower
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8
2nd level coiling of the beads into a helical array
30nm fiber = chromatin
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9
Radial loop domains
interaction between 30-nanometer fibers and nuclear matrix
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10
Euchromatin
DNA that is undergoing normal packing
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11
Heterochromatin
highly condensed in comparison to euchromatin
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12
Features of DNA
Double stranded

Antiparallel strands

Right-handed helix

Sugar-phosphate backbone

Bases on the inside

Stabilize H-bonding

Specific base pairing

About 10 nucleotides per helical turn
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13
Chargoff's rules
A pairs with T

G pairs with C

Keeps width consistent
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