DNA
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13 Terms
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Electrostatic action
________ between the positive charge histone and the negative phosphates of the DNA are an important stabilizing force in maintaining chromatin structure.
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Heterochromatin
________: highly condensed in comparison to euchromatin.
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Euchromatin
________: DNA that is undergoing normal packing.
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Radial loop domains
________: interaction between 30- nanometer fibers and nuclear matrix.
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Major groove
________: proteins bind to affect gene expression.
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Major groove
proteins bind to affect gene expression
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Minor groove
narrower
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2nd level coiling of the beads into a helical array
30nm fiber = chromatin
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Radial loop domains
interaction between 30-nanometer fibers and nuclear matrix
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Euchromatin
DNA that is undergoing normal packing
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Heterochromatin
highly condensed in comparison to euchromatin
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Features of DNA
Double stranded
Antiparallel strands
Right-handed helix
Sugar-phosphate backbone
Bases on the inside
Stabilize H-bonding
Specific base pairing
About 10 nucleotides per helical turn
Antiparallel strands
Right-handed helix
Sugar-phosphate backbone
Bases on the inside
Stabilize H-bonding
Specific base pairing
About 10 nucleotides per helical turn
13
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Chargoff's rules
A pairs with T
G pairs with C
Keeps width consistent
G pairs with C
Keeps width consistent