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carbonyl condensation reactions
reaction of one carbonyl compound with another
makes carbon-carbon bonds
allows for the synthesis of large molecules from smaller subunits
part of most metabolic pathways
special class of alpha-substitution reactions
takes advantage of the ability of carbonyl compounds to act as both nucleophiles and electrophiles
adol reaction
base catalyzed condensation of an aldehyde or ketone with itself
reversible process
results in formation of beta-hydroxy carbonyl
enolate is formed in low concentration
success of reaction depends on steric (more hindered = equilibrium more left)
fairs product when mono substituted acetaldehyde are used (unbranded at alpha position)
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