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what is threshold?
the membrane potential at which an action potential is triggered
what threshold value does the prof use?
about -55 mV
what happens when threshold is reached?
voltage-gated sodium channels open
what is the difference between ligand-gated and voltage-gated channels?
ligand-gated channels open when neurotransmitter bonds; voltage-gated channels open hen membrane voltage changes enough
why is opening voltage-gated sodium channels a point of no return?
sodium rushes in, causing a large depolarization that triggers nearby channels
where does the action potential usually begin?
near the axon hillock, at the cell body-axon interface
how does an action potential propagate?
one depolarized region triggers voltage-gated channels in the adjacent region, moving the signal down the axon
why is an action potential like a domino effect?
once on region activates, it triggers the next region
why is action potential signalling “all-or-none”?
once threshold is reached, the full action potential occurs