proteins lecture 1

COPD

Enlargement of the aveoli and destruction of the cell walls in the lungs.

Enzyme imbalance in the lungs leads to…

destruction of lung tissue and loss of elasticity.

Alpha-1 antitrypsin (AAT)

Protein crucial for protecting the lungs from the destructive effects of enzymes like elastase.

Elastase

Serine protein that breaks down other proteins into smaller proteins.

Antitrypsin

Protein that blocks the active sites of enzymes, preventing the breakdown of elastin.

Inflammation

Result of higher levels of elastase due to the absence of antitrypsin, leading to inflammation in the lungs.

Augmentation therapy

Providing individuals with AAT derived from human plasma to inhibit excessive elastase activity.

Proteins

Make up 50% of the dry weight of a cell and serve as building blocks and molecular tools.

Importance of proteins

In the functional scheme of life, proteins are more important than genes due to their large variety of functions.

causes of copd

absence of the  normal inhibitor of  human neutrophil  leukocyte elastase- a proteolytic enzyme in our bodies

COPD can be linked to a genetic condition where the body doesn't produce enough of a protein called ..

alpha-1 antitrypsin  AAT

what blood cells is elatase made of

white blood cells

what the of protein is elastase

a serine protein- breaks down other proteins into smaller proteins

natural inhibitor of elastase

Alpha-1 antitrypsin