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Name the parts of the small intestine from the end of the stomach to the beginning of the large intestine
Name the parts of the large intestine from the end of the small intestine to excretion
pyloric sphincter → duodenum → jejunum → ileum → ileocecal valve
→ cecum → ascending colon → transverse colon → descending colon → sigmoid colon → rectum → anus
what is the difference between an acute and chronic GI bleed
acute = perforation of intestines from foreign object
chronic = originating from a disease
what is the difference between hematochezia and melena
hematochezia comes from the lower GI tract, and is often bright right
melena is often dark red or black, and comes from the upper GI tract. People with melena can have low hemoglobin/hematocrit and orthostatic hypotension
what rph can you use for a GI bleed, and which one is preferred (what dose for the preferred one)
Tc99m RBCs (preferred) (15-30mCi pertechnetate)
Tc99m SC
what is the MOL of Tc99m RBCs to the GI bleed
extravasation into the intraluminal spaces
how should you position patient for a GI bleed scan
patient supine with xyphoid and pubic symphysis in FOV
where can you find unbound pertechnetate in a GI bleed
stomach, kidneys, gastric mucosa, bladder, small bowel, colon
what is the best method of tagging blood for a GI bleed
ultratag
what are contraindications of a GI bleed scan
barium
not actively bleeding
chronic occult GI bleeding (rate of bleeding too low for detection)
what physiological factors can cause false positives or negatvies in GI bleed scans and interpretation
full bladder block sigmoid/rectum (false -)
urine in renal pelvis of transplanted kidney (false +)
aneurysm (false +)
what will small bowel bleedings look like
rapid serpidimous movement
GI bleed studies can detect bleeding rates as low as _____ - _____ ml/min
0.04 - 1ml/min
what procedure has a >90% accuracy of making a diagnossi of an upper GI. bleed
endoscopy
name two therapeutic interventions for a GI bleed
coagulation via cautery, heat, laser
mechanical therapy via clips, bands
what is Meckel’s Diverticulum, when does it develop, and what does it develop from
a small sac that forms in the ileum, develops at Wk 5 from the vestigial remnant of yolk stalk of embryo
name all the “2s” in Meckels
it’s 2in average
2ft from ileocecal valve
in 2% of population
complications in 2% of that 2% population
symptomatic by age 2
what are the indications of Meckel’s study
find ectopic gastric mucosa
explain GI bleeding
explain blood in feces
explain abdominal pain
what rph do you use for Meckel’s and what dose (adult and ped)
8-12mCi Tc99m pertechnetate
0.05mCi/kg pediatric
what are the contraindications of a Meckel’s scan
actively bleeding
recently got potassium perchlorate
bowel irritants within 24hr (false +)
barium sulfate studies (false -)
tagged RBCs 24hr prior
what is the patient prep for Meckel’s
NPO 2-4hr
cimentidine dose and purpose
20mg/kg/day for 2 days prior to Meckel’s test
blocks release of pertechnetate
Pentagastric purpose and method of administration
increase mucosal uptake of pertechnetate
give 15min before test
Glucagon purpose and method of administration
lowers small bowel motility
give 10min post injection
how should you position a patient for a Meckel’s study
patient supine with xyphoid and pubic symphysis in FOV
when should ectopic gastric mucosa show up on a Meckel’s study
at the same time as normal gastric mucosa (30-60min)
what could cause a false - in a Meckels study
no gastric mucosa in the Meckel’s Diverticula
% esophageal reflux formula
(esophagus cts - esophagus bkg cts) / (max stomach cts) x 100%
Esophagus bkg cts formula
(bkg cts ROI / bkg cts pix) x esophagus cts pix
geometric mean formula
√ANT cts x POST cts
% gastric empty formula
(GM at T0 - GM at T) / (GM at T0)
% gastric remains at T formula
GM at T / GM at T0 x DF
primary perstalsis vs seconday peristalsis
primary peristalsis controls food from pharynx → esophagus → stomach
secondary peristalsis occurs in esophageal body in response to refluxed blood
what things can cause GERD
chocolate
smoking
alcohol
fatty foods
what are two tests besides NM that can evaluate for GERD
endoscopy
esophagram
what are the indications of esophageal reflux NM test
determine presence/absence of GERD/pulmonary aspiration
eval regurgitation/vomitting
diagnose/eval reflux
eval therapy
what are the contraindications of esophageal reflux NM test
recent NM study
pregnant/breastfeeding
patient prep for esophageal reflux
NPO 4hr or overnight
what rph and dose do you use for esophageal reflux study
0.5-2mCi Tc99m SC in 150-300mL orange juice, milk, formula, followed by 30mL water to wash it down
when do you image for esophageal reflux studies
15min after drinking
2-4hr/24hr is lung aspiration suspected
what % reflux for
normal
intermediate
abnormal
nornormal </=3%
intermediate 3-4%
abnormal >4%
what are the indications for a Milk scan
eval children w/ asthma, chronic lung disease, aspiration, pneumonia, anatomic abnormalities
negative barium swallow study
what is the rph and dose for a Milk Study
0.25-1mCi Tc99m SC or Tc99m/In111 DTPA (older children) given with liquid
when do you image for a milk scan
immed
2hr
4hr
12-24hr for aspiration suspection
must scan lungs @24hr
what are the 4 functions of the stomach
SARM
secretion
antibacterial barrier
reservoir
motility
name three advantages of a gastric empty study
gives % empty/retention
low RA dose
can measure solids/liquids
non-invasive
what main thing does the rate of emptying depend on (plus 2 or 3 more factors)
VOLUME
calories
concentration of nutrients
salinity
acidicty
what is the standard gastric empty meal
4oz egg whites, 120mL water, 2 slices white toast, 30mg jelly
what are the indications of a gastric empty test
determine delayed/rapid gastric empty quauntitatevely
eval obstructions
eval symptoms
eval weight loss
what are the contraindications of a gastric empty study
allergy to any part of meal
hypoglycemia (<40mg/dL)
hyperglycemia (>275mg/dL
what is the patient prep for gastric empty study
NPO 4-6hr
stop prokinetic or delaying agent 2 days prior
no smoking
diabetic patients take small portion of insulin dose in morning with meal
what is the adult and pediatric dose for solid gastric empty test
0.5-2mCi Tc99m SC
0.25-0.5mCi Tc99m SC (ped)
what is the dose for a liquid study (liquid only and dual)
liquid only - 500uCi Tc99m DTPA
dual - 125uCi In111 DTPA
300mL water
what does a lack of GM correction cause?
a) rate overestimation
b) rate underestimation
c) anatomic innacuracy
b
what are the phases of gastric emptying
lag phase
prologned phase
slower phase
what are two possible cuases of both delayed and accelerated gastric empty
delayed
surgery
anorexia
accelerated
vagotomy
hyperthyroidism
whats the gold standard for evaluating size and shape of kidneys
US
where are the kidneys
between T12 and L3
name three functions of the kidney
urine formation
regulate BP
waste excretion
what is the parenchyma of kidney made up of, and what do those elements contain
renal cortex - glomeruli
renal medulla - renal pyramids/renal columns
hilum - renal pelvis
what produces renin and where is it
juxtaglomerular apparatus, between the afferent and efferent arterioles
define ERPF and the normal range
effective renal plasma flow is the amount of plasma flowing to the parts of kidney that have a function in urine production (600mL/min)
define GFR and normal ranges
volume of water and solutes filtered out of plasma thru glomerular capillary walls per unit of time (120-125mL/min)
what % of cardiac output goes to the kidneys
20-25%
what are the 3 steps of urine production
1) filtration by glomerulus
2) tubular reabsorption
3) tubular secretion
what rph is a functional glomerular filtration agent
Tc99m DTPA
what rph is a functional tubular secretion agent and what is the dose
1-5mCi Tc99m MAG3
what is a morphological kidney rph and what is the dose
Tc99m DMSA
3-5mCi
0.05mCi/kg (ped)
what are the indications for a renography
assess renal function
eval acute/chronic renal failure
determine % function of each kidney
eval function of transplanted kidney
what are the contraindications of a renography
recent NM study (48)
renal arteriogram a few days before
pregannt/breastfeeding
what is the most important patient prep for renographys
hydration day before, morning of, and 1hr-30min before test
how should you position a patient for a renography
patient supine, find xiphoid, umbilicus, pubis symphysis, and sides in FOV
what four things should a tech evaluate during a renography
FASC
function
anatomy
symmetry
collecting system patency
% Lt kidney function formula
net cts in Lt. ROI (bkg corrected) / (net cts in Lt. ROI (bkg corrected) + net cts in Rt. ROI)
what % kidney function indicates abnormality
</=40%
what are the three phases of kidney imaging and how long are they
1) perfusion (30-60sec)
2) cortical/tubular concentration (1-5 min)
3) excretion (5-20min)
what are the indications for a diuretic renography
obstructive vs nonobstructive hydronephrosis
eval renal obstructive nephropathy
monitor therapy effect
what are 4 nonobstructive causes of hydronephosis
PIVC
previous obstruction
infection (UTI)
vesicouretal reflux
congenital abnormalities
what is the diuretic renography pediatric dose with or without flow
with - 0.15mCi Tc99m MAG3
w/o - 0.10mCi Tc99m MAG3
when do you inject furosemide for a diuretic renography
when collecting systems are full (15-20min)
what could cause mechanical obstruction false positives
dehydration
full bladder
reflux
large renal pelvis
infiltration
what is the purpose of a captopril renal scan
detect patients w/ RAS as the cause of hypertension and predict the curability of it
what are two common causes of RAS
atherosclerosis
fibromuscular dysplasia
why could RAS cause HTN?
decrease afferent arteriolar BP/perfusion pressure →
stimulate renin secretion by juxtaglomerular apparatus →
renin turns angiotensin → angiotensin I
ACE turns angiotensin I → angiotensin II
angiotensin II → vasoconstriction of efferent arteriole (balancing GFR)
angiotensin II → aldosterone secretion from adrenal glands
aldosterone → sodium/water retention, increased blood volume
INCREASED BLOOD PRESSURE
what could cause RVH false positives
hypotension induced during study induces oliguria/cortical retention
dehydration
bladder distension
patient prep for ACEI renography
liquid only 4hr before
no diuretics 3 days
no ACEI 4-7 days
name two blood tests related to kidney function
BUN
creatinine (normal <1.2mg/dL)
what are the indications of morphological renal study
acute vs chronic pyelonephritis
eval renal cortex
identify scarring
eval/localize renal mass
what is the patient prep for morphological renal imaging
hydrate night before/morning of/.5-1hr before test
void before test
no diuretics 24hr before
what is the procedure for morpholgical renal imaging
inj. Tc99m MAG3
wait 2-4hr
image POST using LEHR
or
patient prone, image POST using pinhole
name 3 pseudotumors
column of bertin
suprahilar hump
dromendary humps
what could acute polynephritis look like on morphological renal imaging
1) focal cortical defects
2) multifocal defects
3) diffusely decreaed actvity
where is a transplanted kidney located, and how does it get blood supply
anterior lilac fossa
hypogastric artery and external iliac vein
what is the indication for transplanted kidney imaging
eval kidney function and GU system in renal transplant patients
name three complications of renal transplant
1) acute tuberlar necrosis
2) acute/chronic rejection
3) urinomas
what is a radionuclide cystography for
eval and follow up of children w/ suspected vesicouretal reflux
what rph and dose do you use for radionuclide cystogragraphyphy
0.5-1mCi Tc99m pertechnetate, SC, or DTPA
what is the general proceuure for cystography
clamped IV bag of saline attatched to catheter
put tracer in catheter followed by saline
record filling volume when reflux is first observed
record pre-void statics
get dynamic images while patient pees in bed pan
get post-void statics
how to you calculate estimated bladder volume
(age in yr +2) x 30mL
define
horshoe kidney
polycystic kidney
ptotic kidney
hydronephrosis
horshoe kidney- bottoms of kidneys joined
polycystic kidney - multiple cysts on kidney
ptotic kidney - mobile kidney
hydronephrosis - dilation of reanl pelvis + ureters
what is the thyroid derived from
the ventral wall of the primitive pharynx