L19 Antibody-Drug Conjugates 1

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Last updated 2:27 PM on 5/5/26
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9 Terms

1
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What are antibody-drug conjugates, ADCs

Lets you deliver a highly toxic drug to a specific site

<p>Lets you deliver a highly toxic drug to a specific site</p>
2
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Post-translational modifications

They allow the production of a vast number of different proteins

<p>They allow the production of a vast number of different proteins </p>
3
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Lab-based PTMs

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PTMs - adding a reactive handle

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Uses of PTMs

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Important points with PTMs

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ADCs linker function

needs to release the drug at the right moment

<p>needs to release the drug at the right moment</p>
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Main uses of ADCs

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Mode of action of ADCs with toxic payloads

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