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tx blepharitis
Topical Antibiotics (Monotherapy)
• Polysporin, Erythromycin, or bacitracin
tx hordeolum
warm compress
abx monotherapy if resistant to conservative management
cephlexin or Amoxiccillin
clindamycin if penicillin allergy
pseudodentrites on fluroescein
HZV ophthalmicus
dendritic ulcers on fluorescein
HSV keratitis
tx allergic conjunctivitis
Naphazoline/pheniramine 0.025%/0.3% QID
tx viral conjunctivitis
Artificial tears x 1 week
Cold compress
tx HSV/HZV conjunctivitis
acyclovir (preferred for immunocompromised), ganciclovir, or valacyclovir
tx bacterial conjunctivitis
staph/strep: erythromycin
pseudomonas: levofloxacin
GC/chlamydia: ceftriaxone + doxy + erythromycin
tx corneal ulcer
moxi or cipro
tx for periorbital cellulitis outpatient
amox-clavulanate (augmentin) + clindamycin/bactrim
cefpodoxime if penicillin allergy
tx for periorbital cellulitis inpatient
pick 1
ampicillin-sulbactam (unasyn)
pipercillin-tazobactam (zosyn)
ceftriazone if allergy
pick 1
vancomycin
tx for orbital cellulitis
same as periorbital
pick 1
ampicillin-sulbactam (unasyn)
pipercillin-tazobactam (zosyn)
ceftriaxone if allergy
pick 1
vancomycin
use amphotericin if DM or immunocompromised
what imaging is done for suspected intraocular FB retention
ocular US or CT orbit
tx corneal laceration
no contacts: erythromycin ointment
contacts: levofloxacin solution
what IOP indicates acute angle glaucoma?
>20
tx acute angle glaucoma
Decrease production of aqueous humor
β-blocker Timolol ophthalmic 0.5%
Carbonic anhydrase inhibitors (Pick 1): Dorzolamide (Trusopt) 2% or Acetazolamide
Facilitate outflow of aqueous humor
Topical α-adrenergic agonist (Pick 1): Brimonidine (alphagan) 0.2% or Apraclonidine 1%
Muscarinic cholinergic agonist (Pick 1): Pilocarpine 1%–2% q15min, the q4h
Reduce Inflammation (Pick 1)
Steroids ophthalmic: Prednisolone acetate 1% q15min x4, then q1h
Reduce volume of aqueous humor (Controversial)
Mannitol 1-2 g/kg IV given over 45 minutes
u/l eye pain, blurred halo vision, N/V, abrupt onset, hazy cornea
acute angle glaucoma
associated w/ MS, monocular vision loss, painful eye movements
optic neuritis
which condition causes pulfrich effect and red desaturation test
optic neuritis
what is the imaging of choice for optic neuritis
MRI/MRA of brain and orbits
what finding on US indicates optic neuritis
papilledema > 5mm diameter
tx for optic neuritis
IV Methylprednisolone
sudden painless monocular vision loss w/ cherry red spot
central retinal artery occlusion
sudden painless monocular vision loss w/ blood and thunder fundus
central retinal vein occlusion
imaging for CRAO/CRVO? which is gold standard?
CT angiogram head and orbit (gold)
carotid US
pale retina?
CRAO
CRAO tx if temporal arteritis etiology (elevated ESR/CRP)
Methylprednisone
general tx for CRAO
Alteplase (TPA)
tx for CRVO
Bevacizumab Intravitreal (anti-VEGF)
painless abrupt vision loss w/ floaters, flashes of light, curtain, hazy retina
retinal detachment
what diagnostic is needed for retinal detachement
ocular US: to determine maculo on vs macula off
how do you position retinal detachment pts?
superior visual field defect/detachment: lay supine
inferior visual field defect/detachment: elevate head
general management otitis externa
analgesics
1:1 dilution NS to 3% hydrogen peroxide
otitis externa abx therapy
No Concomitate TM perforation
• Ciprofloxacin-hydrocortisone
• Ciprofloxacin-dexamethasone
• Neomycin/polymixin B/hydrocortisone
Concomitant TM perforation
• Ofloxacin (Floxin) 5gtt BID
Immunocompromised
Systemic Antibiotics: Ofloxacin or Ciprofloxacin PO
tx malignant otitis externa
adult monotherapy
cefepime IV
Piperacillin-Tazobactam (Zosyn) IV
Imipenem IV
levofloxacin or ciprofloxacin if beta-lactam allergy
peds dual therapy
1 from above (beta-lactam w/ antipseudomonal)
gentamycin IV
tx for otitis media
WASP b/c most viral
monotherapy abx if sx worse for 48-72 hrs
1st line: amoxicilin, azithromycin, clindamycin (if PCN allergy)
2nd line if recent abx use:
Amoxicillin-clavulanate (Augmentin)
Cefuroxime
Cefpodoxime
Ceftriaxone
imaging needed to dx mastoiditis
CT Mastoid w/ IV contrast
tx mastoiditis
Broad-spectrum gram (+) coverage (Pick 1)
Ampicillin-Sulbactam (Unasyn) IV
Ceftriaxone (Rocephin) IV
Risk of pseudomonas
Piperacillin-Tazobactam IV
Cefepime 2g IV
Severe PCN allergy = Aztreonam IV
MRSA Coverage (Pick 1)
Clindamycin IV
Vancomycin
tx dental caries
chlorhexedine rinse
amoxicillin or clindamycin (if PCN allergy)
what imaging is needed for gingival or periodontal abscess
soft tissue CT with IV contrast
tx for gingival and periodontal abscess
I & D followed by chlorhexidine
tx for gingival & periodontal abscess
Outpatient: uncomplicated (monotherapy)
Amoxicillin-Clavulanate (Augmentin)
PCN Allergy
Doxycycline
Clindamycin
Inpatient: complicated (monotherapy)
Ampicillin-sulbactam IV
Concern for pseudomonas: Piperacillin-tazobactam IV
PCN Allergy
Ceftriaxone or Cefepime IV (Pseudo)
Clindamycin IV
raised tongue, woody-brawny floor swelling, tongue protrusion, dysphonia
ludwig’s angina
imaging needed for ludwig’s angina
CT w/ contrast
tx ludwig’s angina
triple therapy
Piperacillin-Tazobactam (Zosyn) or Cefepime or Meropenem
clindamycin
vancomycin
tx sinusitis general
hypertonic saline
Vasoconstrictors: Phenylephrine or Oxymetazoline (Afrin)
antihistamines
1st Generation “drowsy” Diphenhydramine (Benadryl)
2nd Generation “nondrowsy”: Loratadine (Claritin), cetirizine (Zyrtec)
steroids: Fluticasone propionate (Flonase)
tx sinusitis abx
monotherapy
Amoxicillin-Clavulanate (Augmentin)
Clindamycin (PCN allergy)
doxy (PCN allergy)
gold standard: Mucormycosis
Histopathology:Â but do not wait for confirmation to treat
tx Mucormycosis
surgical debridement
Hyperbaric Oxygen Therapy
Fe Chelation: Deferasirox
antifungal: Amphotericin B
tx pharyngitis outpatient
No antibiotic use in last 3 months: Monotherapy
Bicillin IM x 1 (Better for noncompliant patients)
Amoxicillin x 10 days
Penicillin Allergy
Clindamycin 300mg QID
Azithromycin (Z-Pack)
Antibiotic use in last 3 months
Amoxicillin-clavulanate (Augmentin)
tx pharyngitis inpatient
Monotherapy
Ampicillin-sulbactam IV
Piperacillin-Tazobactam IV (Pseudomonas)
Ceftriaxone or Cefepime IV (Pseudomonas + allergy)
Clindamycin IV (PCN allergy)
tx peritonsillar abscess general
needle aspiration
I&D
steroids
Methylprednisolone
Dexamethasone
tx peritonsillar abscess
outpatient monotherapy
Amoxicillin-clavulanate
Clindamycin (allergy)
inpatient monotherapy
Ampicillin-Sulbactam (Unasyn) IV
Piperacillin-Tazobactam IV
clindamycin (allergy)
tx Retropharyngeal Abscess
Dual Therapy
1, Gram (+/-) Broad spectrum (Pick 1)
Ampicillin-Sulbactam (Unasyn) IV
Pipercillin-Tazobactam (Ps)
Ceftriaxone or Cefepime (Ps + allergy)
MRSA Coverage (Pick 1)
Vancomycin IV
Clindamycin IV