2 Haematopoiesis

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These flashcards cover the key terms and concepts related to hematopoiesis, including processes of erythropoiesis and leukopoiesis.

Last updated 7:35 AM on 4/8/26
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7 Terms

1
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Hematopoiesis

The formation of the formed elements of blood, including red blood cells, white blood cells, and platelets.

2
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What is a haematopoietic stem cell (HSC)?

A multipotent stem cell in the red bone marrow that can differentiate into all types of blood cells, forming either myeloid or lymphoid lineages.

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What are the two main lineages of blood cells derived from HSCs?

  • Myeloid lineage → RBCs, platelets, granulocytes, monocytes

  • Lymphoid lineage → B cells, T cells, NK cells

4
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What is erythropoiesis?

The production of red blood cells (RBCs) in the bone marrow, stimulated by erythropoietin (EPO) from the kidneys in response to low oxygen levels.

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What is leukopoiesis?

The production of white blood cells (WBCs) in the bone marrow, regulated by cytokines and growth factors.

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How does erythropoietin (EPO) regulate RBC production (especially if O2 is low)?

The kidneys detect low oxygen → release EPO → stimulates erythropoiesis in the red bone marrow → increases RBCs → improves oxygen transport.

7
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Key difference between erythropoiesis and leukopoiesis?

  • Erythropoiesis → RBCs, controlled mainly by EPO

  • Leukopoiesis → WBCs, controlled by cytokines and growth factors.