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What happens to the diaphragm during inspiration?
Contracts
What happens to the thoracic cavity during inspiration?
Expands
What happens to lung volume during inspiration?
Increases
What happens to intrapulmonary pressure during inspiration?
Decreases
What direction does air move during inspiration?
Into the lungs
What happens to the diaphragm during expiration?
Relaxes
What happens to the thoracic cavity during expiration?
Shrinks
What happens to lung volume during expiration?
Decreases
What happens to intrapulmonary pressure during expiration?
Increases
What direction does air move during expiration?
Out of the lungs
When lung pressure is less than atmospheric pressure, what happens?
Air enters the lungs
When lung pressure is greater than atmospheric pressure, what happens?
Air exits the lungs
Big chest = ?
Low pressure = air enters
Small chest = ?
High pressure = air exits
What is the relationship between volume and pressure according to Boyle's Law?
They move in opposite directions
If volume increases, what happens to pressure?
Pressure decreases
If volume decreases, what happens to pressure?
Pressure increases
Which law explains how breathing works?
Boyle's Law
What happens to pressure when lung volume increases?
Pressure decreases
In the lungs, oxygen moves from where to where?
Alveoli to blood
In the lungs, carbon dioxide moves from where to where?
Blood to alveoli
In the tissues, oxygen moves from where to where?
Blood to cells
In the tissues, carbon dioxide moves from where to where?
Cells to blood
At the lungs, oxygen does what?
Enters the blood
At the lungs, carbon dioxide does what?
Leaves the blood
What percentage of oxygen is attached to hemoglobin?
98.5%
What percentage of oxygen is dissolved in plasma?
1.5%
What percentage of carbon dioxide is transported as bicarbonate?
70%
What percentage of carbon dioxide is attached to hemoglobin?
23%
What percentage of carbon dioxide is dissolved in plasma?
7%
What is the major transport form of oxygen?
Attached to hemoglobin
What is the major transport form of carbon dioxide?
Bicarbonate (HCO3-)
Where are central chemoreceptors located?
Medulla
What do central chemoreceptors mainly respond to?
CO2 and H+
Where are peripheral chemoreceptors located?
Carotid arteries and aortic arch
What do peripheral chemoreceptors respond to?
O2, CO2, and H+
What is the biggest driver of breathing?
CO2
What causes respiratory acidosis?
Too much CO2
What happens to H+ during respiratory acidosis?
Increases
What happens to pH during respiratory acidosis?
Decreases
What causes respiratory alkalosis?
Too little CO2
What happens to H+ during respiratory alkalosis?
Decreases
What happens to pH during respiratory alkalosis?
Increases
CO2 increases = ?
pH decreases
CO2 decreases = ?
pH increases
What is tidal volume (TV)?
Normal breath (~500 mL)
What is inspiratory reserve volume (IRV)?
Maximum inhale (~3000 mL)
What is expiratory reserve volume (ERV)?
Maximum exhale (~1100 mL)
What is residual volume (RV)?
Air remaining after maximal exhalation (~1200 mL)
Formula for inspiratory capacity (IC)?
TV + IRV
Formula for functional residual capacity (FRC)?
ERV + RV
Formula for vital capacity (VC)?
IRV + TV + ERV
What is vital capacity?
Amount of exchangeable air
Formula for total lung capacity (TLC)?
IRV + TV + ERV + RV
What is total lung capacity?
Maximum amount of air in the lungs
What structures make up the conducting zone?
Nose to terminal bronchioles
Function of the conducting zone?
Move air
Does gas exchange occur in the conducting zone?
No
What structures make up the respiratory zone?
Respiratory bronchioles, alveolar ducts, alveoli
Function of the respiratory zone?
Gas exchange
Where does gas exchange occur?
Alveoli
Where is pseudostratified ciliated columnar epithelium found?
Trachea and bronchi
Function of pseudostratified ciliated columnar epithelium?
Moves mucus upward
Where is simple squamous epithelium found?
Alveoli
Function of simple squamous epithelium?
Gas exchange
Function of stratified squamous epithelium?
Protection
What happens when Ppul is less than Patm?
Air enters lungs
What happens when Ppul is greater than Patm?
Air exits lungs
What happens when Ppul equals Patm?
No airflow
Which respiratory center establishes the basic breathing rhythm?
VRG
Function of the DRG?
Modifies breathing rhythm
Function of the pons in respiration?
Smooth transition between inhalation and exhalation
What is oxyhemoglobin?
Hemoglobin carrying oxygen
What is deoxyhemoglobin?
Hemoglobin without oxygen
How many oxygen molecules can one hemoglobin carry?
4
What characterizes asthma?
Airway constriction and mucus production
What is a major effect of tuberculosis?
Scarring and damage to lung tissue
What is atelectasis?
Lung collapse
What is hypoxia?
Low oxygen
What is anoxia?
No oxygen
What is eupnea?
Normal breathing
What is apnea?
No breathing
What is dyspnea?
Difficult breathing
What happens during hyperventilation?
Too much CO2 lost
What happens during hypoventilation?
CO2 retained
What is hyperpnea?
Increased depth and rate of breathing during activity
Where does oxygen diffuse in the lungs?
Alveoli to blood