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circulatory system functions
carries blood back and forth between the heart and body
exchange nutrients, wastes, gases
transport hormones, enzymes, gases
blood volume transported to maintain homeostasis
arteries
thick muscular walls found beneath skin
carry oxygenated blood from heart to tissues
arterioles
small arteries that connect to capillaries, deliver blood to capillaries
metarterioles: form branches into capillary bed connecting arterioles to capillaries
tunica media contains few layers of smooth muscle (2-3 layers)
capillaries
small blood vessels with thin walls
site of substance exchange btwn blood and body tissues
veins
thin walls; contains valves preventing backflow of blood
closer to skin surfaces
convey blood from tissues back to heart
venules
Small veins collecting blood from capillaries
connect capillaries to larger veins
Tunica media contains only a few smooth muscle cells & scattered fibroblasts
vaso vasorum
small blood vessels supplying blood to cells of the walls
tunica externa of the arteries and veins
tunica intima
internal layer
made of endothelial cells (simple squamous), basement membrane, and lamina propria made up of elastic membrane separating the intima from the media
tunica media
middle layer
made of smooth muscles, elastic and collagen fibers
vasoconstriction decreases BV diameter and vasodilation increases BV diameter
tunica externa
outside layer
made of dense connective tissues, loose connective tissues
elastic arteries
Large arteries with more elastic fibers and less smooth muscle (6-7 layers)
receive blood under pressure and propel it onward
aka conducting arteries: conduct blood from the heart to medium sized muscular arteries
muscular arteries
Medium-sized arteries with more muscle than elastic fibers in tunica media
Capable of greater vasoconstriction and vasodilation to adjust rate of flow
aka distributing arteries: they direct blood flow
brachial and axillary
continuous capillaries
Small intercellular clefts are gaps between neighboring cells
skeletal & smooth tissue and lungs
Fenestrated capillaries
Mid size intercellular clefts
Contain large fenestra allowing molecules to leave
kidneys, small intestine, choroid plexuses, endocrine glands
Sinusoids
very large gap (intercellular cleft)
Allow for leakage of molecules
liver, bone marrow, spleen, anterior pituitary gland, & parathyroid gland
pulmonary circulation
transports deoxygenated blood from the right side of the heart to the lungs for oxygenation
Systemic circulation
Transport blood between the heart and other organs
left side heart to body & back to heart
Fetal circulation
from fetal heart through umbilical cord to placenta & back
Coronary Circulation
Blood supply to and from the heart
pulmonary circulation steps
Starts off from right atrium (deoxygenated blood) → right ventricle → pulmonary trunk → left/right pulmonary arteries → lungs (alveoli) → out through pulmonary veins (oxygenated blood → exits each lungs; right and left → and into heart
aorta
supplying arms, head, lower limbs, and all viscera with O2 from the lungs
left and right external carotid arteries
Supplies neck and face
tongue, mouth, thyroid gland, larynx, middle and inner ear, lower jaw, upper jaw, nose
left and right vertebral artery
supplies blood to the upper spinal cord, brain stem, cerebellum, posterior part of the brain, posterior neck, upper limbs
left subclavian artery
transport blood to the upper limb
basilar artery
Supplies brain stem, cerebellum, thalamus, parietal lobes
internal thoracic artery
supplies thoracic and abdominal walls
Splenic artery
supplies spleen, pancreas, and stomach
Left gastric artery
supplies stomach
Common hepatic artery
supplies liver, gall bladder and small intestines
Superior mesenteric artery
supplies small intestines, cecum, ascending colon and transverse colon
Phrenic artery
supplies diaphragm
L/R suprarenal arteries
supplies adrenal glands
L/R renal artery
supplies kidneys
L/R gonadal artery
supplies ovaries and testes
lumbar artery
supplies back and abdominal wall
Inferior mesenteric
supplies descending colon, sigmoid colon, rectum
Right/Left external artery
Common iliac artery
supplies lower limb, anterior abdominal wall
Right/Left internal artery
Common iliac artery
supplies pelvic organ, genitalia and hip
circle of willis
Anterior communicating Artery
Anterior cerebral Artery
Middle cerebral Artery
Internal Carotid Artery
Posterior communicating artery
Posterior cerebral artery
Anterior communicating Artery
Connect left/right cerebral hemispheres
Supplies the fornix, optic chiasm, and hypothalamus
Anterior cerebral Artery
Supplies medial and superior portion of frontal lobe, anterior portion of parietal lobe, choroid plexus, lower portion of pons
Middle cerebral Artery
Supplies frontal lobe, lateral side of temporal lobe, and parietal lobe
motor portion of face, throat and hand
largest branch of internal carotid artery
Internal Carotid Artery
Supplies blood to brain
Posterior communicating artery
alternate supply in case the iCA is blocked
Supplies thalamus, hypothalamus, optic chiasma
Posterior cerebral artery
supplies occipital lobe (visual area), inferior of temporal lobe, thalamus
superior vena cava
drains the head and upper extremities
inferior vena cava
drains the abdomen, pelvis & lower limbs
coronary sinus
large vein draining the heart muscle back into the heart
Cardiac Veins
transports blood from walls of the heart through the coronary sinus into the right atrium
Brachiocephalic vein
drains blood from the head, neck, arms back to the heart
L/R External jugular veins
Drain blood from posterior head and neck
L/R subclavian vein
drain right side of the limbs and into the brachiocephalic veins
L/R Internal jugular veins
Drains blood from the anterior head, face and neck
drain into the brachiocephalic veins
R/L internal thoracic vein
drain blood from thoracic and abdominal walls into the R/L brachiocephalic vein
axillary veins
blood from upper limbs, armpit towards the heart
Brachial veins
drains blood from upper arm, between elbow and shoulder
radial veins
drains blood from hand and forearm
ulnar veins
drains medial aspect of the forearm
median cubital vein
returns blood from the forearm
digital vein
carries blood from the fingers
gastric vein
drains blood from stomach
splenic vein
drains blood from spleen and pancreas
hepatic portal veins
drain blood from liver, gallbladder
Superior mesenteric vein
drains from Small intestines, cecum, ascending colon, transverse colon
Inferior mesenteric vein
drains from descending colon, sigmoid colon and upper rectum
L/R lumbar veins
drains posterior abdominal wall
L/R renal veins
drains kidneys
L/R suprarenal veins
drains adrenal medulla
L/R gonadal veins
drains ovaries and testes
L/R phrenic veins
drains diaphragm
L/R external iliac vein
drains lower limb, anterior abdominal wall
L/R internal iliac vein
drains pelvic organs, genitalia, and hip
hepatic portal circulation
collects blood from the veins of the pancreas, spleen, stomach, intestines, and gallbladder and directs it into the hepatic portal vein of the liver before it returns to the heart
laminar flow
blood moving in a smooth streamlined fashion
steady rate in a long smooth vessels
silent sound
turbulent flow
blood flow is irregular and a bit more chaotic
causes murmurs
ex: constriction of bv or an obstruction
blood pressure
the pressure exerted on the walls of a blood vessel
sphygmomanometer
used to measure blood pressure
systolic blood pressure
recorded during ventricular contraction
diastolic blood pressure
recorded during ventricular relaxation
normal blood pressure
120/80
elevated blood pressure
120-129/<80
stage 1 hypertension
130-139/80-89
stage 2 hypertension
≥140/≥90
hypertensive crisis
>180/>120
pulse points
brachial (upper arm)
temporal (temple)
carotid (neck)
radial (wrist)
femoral (inner groin area)
popliteal (back of knee)
axillary (armpit)