CPJE Renal Dosing: Diabetes

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Last updated 7:10 PM on 4/29/26
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16 Terms

1
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Liraglutide (Victoza, Saxenda)

Does it require renal dose adjustment?

Normal: 0.6 mg SQ daily with weekly titration to 3mg

No renal dose adjustment:)

2
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Dulaglutide (Trulicity)

Does it require renal dose adjustment?

Normal: 0.75mg - 1.5 mg SQ once weekly

No renal dose adjustment:)

3
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Exenatide IR (byetta) vs ER (byurdeon)

Contraindicated at what renal functin?

IR (Byetta): CrCL < 30 = DO NOT USE

ER (Byurdeon): eGFR < 45 = DO NOT USE

4
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Lixisenatide (ADLYXIN)

Adlyxin is contraindicated at what EGFR?

eGFR < 15 = DO NOT USE

5
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Semaglutide SQ (wegovy, ozempic)

Does it require renal dose adjustment?

No renal dose adjustment:)

6
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Semaglutide PO (Rybelsus)

Does it require renal dose adjustment?

No renal dose adjustment:)

7
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Sitagliptin (JANUVIA)

Normal: 100mg daily

eGFR < __ = 50mg daily

eGFR < __ = 25 mg daily

Normal: 100mg daily

eGFR < 45 = 50mg daily

eGFR < 30 = 25 mg daily

8
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Linagliptin (Tradjenta)

Does it require renal dose adjustment?

Normal: 5mg daily

No renal dose adjustment:)

9
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Saxagliptin (Onglyza)

Normal: 5mg daily

eGFR < __ = 2.5 mg daily

Normal: 5mg daily

eGFR < 45 = 2.5 mg daily

10
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Alogliptin (NESINA)

Normal: 25mg daily

eGFR < __ = 12.5mg daily

eGFR < __ = 6.25 mg daily

Normal: 25mg daily

eGFR < 60 = 12.5mg daily

eGFR < 30 = 6.25 mg daily

11
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Canagliflozin (INVOKANA)

Normal: 300mg daily

eGFR < __ = 100mg daily

eGFR < __ = DO NOT USE

Normal: 100-300mg daily

eGFR < 60 = 100mg daily

eGFR < 30 = DO NOT USE

12
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Dapagliflozin (FARXIGA)

Should not be used at eGFR < ______

eGFR < 25 = DO NOT USE

13
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Empagliflozin (JARDIANCE)

Should not be used at eGFR < ______

eGFR < 30 = DO NOT USE

14
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Ertugliflozin (STEGLATRO)

Should not be used at eGFR < ______

eGFR < 45 = DO NOT USE

15
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Metformin

eGFR< ___ = okay to CONTINUE

eGFR < ___ = stop metformin

eGFR< 45 = okay to CONTINUE

eGFR < 30 = stop metformin

16
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