Wound care and bariatrics
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11 Terms
what BMI is considered obesity
30 and above
what is ghrelin
hormone responsible for appetite stimulation
obesity is associated with REDUCED ghrelin SUPPRESSION
what hormones are secreted in response to food intake
anorexigenic intestinal hormones
GLP-1
PYY
CCK
involved in digestion, insulin secretion * post-digestive metabolism and satiety
what is leptin
signals body energy stores - inhibits hunger
In PPT with more body fat, leptin levels are elevated
how are most GLP-1s eliminated
renal elimination
adverse effects of GLP-1 agonists
nausea + vomiting
diarrhoea
dyspepsia
injection site reactions
hypoglycaemia
dizziness
cholecystitis
pancreatitis
long term complications of surgery
iron deficiency
calcium and vitamin D deficiency
vitamin b12/1 deficiency
protein deficiency
gallstones
weight regain
(bc low absorption)
pH changes after bariatric surgery
partition of stomach results in decreased production of HCL
may affect bioavailability of drugs/formulations wose absoprtion is pH dependent (e.g iron and calcium)
calcium carbonate vs calcium citrate
carbonate depends on acid for absoprtin; calcium citrate does not
why avoid NSAIDs after bariatric surgery
reduction in gastric volume - inc potential of damage to gastric mucosa