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Apoptosis
a process of programmed cell death marked by cell shrinkage
Capacity
the ability to make decisions
Catecholamine
hormones of the adrenal medulla that are released in response to sympathetic nervous system activity
Energy maintenance theory of aging (EMTA)
based on animal research, this model suggests that persons must maintain higher levels of ATP to sustain longevity
Free radicals
molecules with an unpaired electron in the outer shell of electrons that remain unstable until paired with another molecule
Human needs theory
Maslow surmised that a hierarchy of five needs motivates human behavior: physiologic, safety and security, love and belonging, self-esteem, and self-actualization
Immunomodulation
the effects of various chemical mediators, hormones, and drugs of the immune system
Lipofuscin (LF)
an un-degradable material that decreases lysosomal function; age pigment; a brown pigment found in aging cells relating to oxidative mechanisms
Melatonin
a hormone produced by the pineal gland that is linked to sleep and wake cycles
Mitochondria
parts of a cell that transform organic compounds into energy
Nonstochastic theories of aging
theories stating that a series of genetically programmed events occur to all organisms with aging
Reactive oxygen species (ROS)
short-lived, highly reactive products of mitochondrial oxidative metabolism that destroy proteins, lipids, and nucleic acids
Senescence
the process of growing old
Stochastic theories of aging
theories stating that random events occurring in one’s life cause damage that accumulates with aging
Telomerase
an enzyme that regulates chromosomal aging by its action on telomeres
Telomere
repeated sequences of DNA that protect the tips of the outermost appendages of the chromosome arms