NUCLEOSOME STRUCTURE (Page 31)

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Last updated 2:09 PM on 6/19/26

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; [Who proposed the nucleosome hypothesis and when?]

Roger Kornberg proposed the nucleosome hypothesis in 1974.

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; [What are the core histones?]

Histone 2A (H2A), Histone 2B (H2B), Histone 3 (H3), and Histone 4 (H4).

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; [What is the linker histone?]

Histone 1 (H1).

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; [How is the nucleosome core particle structured?]

Two of each core histone form an octameric nucleosome core particle wrapping ~147bp of DN