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What do ACE inhibitors do?
Prevent the conversion of angiotensin 1 to angiotensin 2
Prevent the conversion of Bradykinin into inactive kinins
What are ACEis used to treat?
High BP
What is the role of Zinc in Ace?
Stabilizes conversion of angiotensin 1 to 2
What are critical interactions with ACE a drug needs?
2 hydrophobic groups
C-terminal negative charge

What is this a backbone of?
ACEi

What type of drug is this?
Sulfhydryl-containing ACE inhibitor

How is this drug given?
PO

What does this drug treat?
HPN and heart failure

When is this drug best taken?
At least 1 hour before a meal

What are the issues with captopril?
Sulfur tastes bad and smells bad

What type of drug is this?
Dicarboxylate ACE inhibitors
What is this a general structure of?

Dicarboxylate ACE inhibitors

What type of drug is this?
Dicarboxylate ACEi

What type of drug is this?
Dicarboxylate ACEi
What type of drug is this?

Phosphonate-containing ACEi