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TLR-3
Double stranded viral RNA
TLR-4
LPS
TLR-5
Flagellin
TLR-7
Single stranded viral RNA
IL-1
Inflammatory cytokine made by macrophages after recognition of PAMPs
TNF-a
Induces blood vessels to be more permeable, enabling cells, fluid and soluble effectors to enter infected tissue.
Il-6
Induces fat and muscle cells to metabolize, generate heat, and raise the temperature in the infected tissue.
CXCL8
Recruits neutrophils from the blood and directs them to the infected tissue
CCL2
Recruits monocytes from the blood and directs them to the infected tissue
IL-12
Recruits and activates NK cells to secrete cytokines that strengthen macrophages response to infection