week 8 platelets mock

1. Primary hemostasis involves:
A. Fibrin clot
B. Platelet plug
C. RBCs
D. WBCs

b

2. Platelets are derived from:
A. Lymphocytes
B. Megakaryocytes
C. Monocytes
D. RBCs

b

3. Endoreduplication is:
A. Cell division
B. DNA replication without division
C. Protein synthesis
D. Cell death

b

4. Platelet size:
A. 1–2 µm
B. 2–4 µm
C. 5–10 µm
D. 10–15 µm

b

5. Dense granules contain:
A. vWF
B. ADP
C. Fibrinogen
D. PF4

b

6. Alpha granules contain:
A. Serotonin
B. ADP
C. vWF
D. Calcium

c

7. First step of platelet function:
A. Aggregation
B. Activation
C. Adhesion
D. Clotting

c

8. Platelet aggregation requires:
A. RBCs
B. Fibrinogen
C. DNA
D. Iron

b

9. Platelet lifespan:
A. 1 day
B. 3 days
C. 9–10 days
D. 20 days

c

10. Aspirin works by:
A. Increasing clotting
B. Blocking COX-1
C. Increasing ADP
D. Increasing calcium

b

define primary hemostasis

formation of platelet plug

list platelet granule types

alpha, dense, lysosomal

describe platelet adhesion

platelets bind collagen via vwf

what is platelet aggregation

platelets stick together via fibrinogen bridges

name 3 aggregation agents

adp, collagen, epinephrine, thrombin, ristocetin