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What is the normal % of blood ejected from the ventricle per beat (EF)?
55-70%
What is contractility?
force of myocardial contraction
What is rate product pressure (RPP, or double product pressure [DPP])?
What is it used for?
HR x SBP
to measure myocardial workload & O2 demand of the heart
What does a higher and lower RPP indicate?
higher RPP = more O2 demand on the heart
lower RPP = lower stress & demand on the heart
What happens with incremental exercise in terms of HR, Q, & BP?
HR, Q, & MAP increases linearly w/ increasing work rate
HR & Q plateaus at 100% VO2max or HRmax
SBP increases, DBP remains fairly intact
What is the new AHA/ACC High BP Guidelines?
normal: <120/80
elevated: SBP 120-129 AND DBP <80
Tx: healthy lifestyle & diet
stage 1: SBP 130-139 OR DBP 80-89
Tx: same as above, and meds in case of high risk
stage 2: SBP ≥140 OR DBP ≥90
Tx: meds
hypertensive crisis: SBP >180 AND/OR DBP >120
need prompt ∆s in meds or immediate hospitalization if Sx’s present
Sx’s: chest pain, back pain, SOB, numbness, weakness, vision ∆s, difficulty speaking
medical emergency
What is hypotension?
What can cause this?
SBP <90 OR DBP <60, inadequate blood flow to heart, brain, & other organs
bed rest, drugs, arrhythmia, blood loss or shock, MI
What is orthostatic hypotension?
How can you assess this?
drop in SBP >20 or DBP >10
assess BP & HR when pt has been supine for 5 min
then have pt stand up, then reassess BP & HR after 3 min of standing
if pt is symptomatic, have them sit down and maybe w/ legs elevated to a reclined position
What are the effects of altitude initially & after acclimatization?
initial: increased HR, Q, BP, normal SV
acclimatization: increased HR, normal Q & BP, reduced SV
What are the CV effects of aquatic therapy?
decreased HR, BP, VO2
increased SV, Q
increased venous return & preload d/t increased hydrostatic pressure
cephalad redistribution of blood flow
What are the respiratory effects of aquatic therapy?
challenges chest expansion
decreased IRV, VC
increased WOB
What are the MSK effects of aquatic therapy?
decreased WB, edema d/t hydrostatic pressure exerted by water
increased mm strength & endurance d/t water resistance
What are the % WB with immersion of C7, xiphoid process, & ASIS?
C7 = 10% BW
xiphoid process = 33%
ASIS = 50%
What are the effects of warm water & cold water with aquatic therapy?
warm: relaxation
cold: reduce pain & inflammation
What are beta blockers?
What does it do and who is it used for?
beta-adrenergic blocking drugs (-olol)
compete w/ epinephrine & norepinephrine for beta adrenergic receptors in the heart
reduce HR & contractility (lower myocardial O2 demand)
will blunt HR during exercise
for pts w/ CAD & HTN
Mnemonic for Borg RPE rating?
13 SHVEM
13 = somewhat hard
15 = hard
17 = very hard
19 = extremely hard
20 = maximal exertion
What is preload?
L ventricular end-diastolic pressure (LVEDP); the amt. of ventricular stretch at the end of diastole
What is afterload?
systemic vascular resistance (SVR); the amt. of resistance the heart must overcome to open the aortic valve and push blood out
higher afterload is not good for us
What are the 5 auscultation landmarks and their locations?
aortic: 2nd IC space, R sternal border
pulmonic: 2nd IC space, L sternal border
Erb point: 3rd IC space, L sternal border
heart murmurs
tricuspid: 4th IC space, L sternal border
mitral (apical): 5th IC space, L midclavicular line
best site if S3 present
point of maximal impulse
What are the S1, S2, S3, S4 heart sounds?
S1: lub, closure of tricuspid & mitral valves (AV valves) → onset of systole
S2: dub, closure of pulmonary & aortic valves (semilunar valves) → onset of diastole
S3: ventricular gallop (S1-S2-S3), ventricular filling into overloaded ventricle after AV valves open
low-frequency turbulence, heard during early diastole
hallmark sign of CHF
S4: atrial gallop (S4-S1-S2), ventricular filling & atrial contraction into stiff ventricle
low-frequency turbulence, heard during late diastole
common in HTN, pulmonary HTN, MI, LV hypertrophy, increased LVEDP, aortic or pulmonary stenosis
What are heart murmurs?
What are the grades?
whooshing or swishing sounds of turbulent blood flow d/t valve disorders
grade 1 = softest
grade 6 = audible w/o stethoscope
What are systolic murmurs?
“lush” instead of “lub”; turbulence b/w S1-S2
d/t valve disease (mitral valve prolapse), aortic stenosis, or may be normal
What are diastolic murmurs?
turbulence b/w S2-S1
d/t aortic & pulmonary regurgitation, mitral stenosis
What is thrill?
abnormal, palpable tremor w/ vascular or cardiac murmur
What is the difference b/w stenotic valve & regurgitant valve?
stenotic valve: impaired opening
regurgitant valve: impaired closing
What is bruit?
Where is this most commonly found?
adventitious sound or murmur (blowing sound) of arterial or venous origin
turbulent blood flow d/t atherosclerosis or partially blocked artery
common in carotid or femoral arteries
What is pericardial friction rub?
high-pitched heartbeat, leathery, scratchy quality
d/t inflammation of the pericardial sac
post-MI pericarditis (Dressler syndrome)
How do you grade pulses?
0 = absent, not palpable
1+ = diminished, barely palpable: reduced SV, cardiogenic shock, increased peripheral resistance, severe CHF
2+ = normal, easily palpable
3+ = full pulse, increased strength
4+ = bounding pulse: increased SV, shortened ventricular systole, reduced peripheral pressure, aortic insufficiency, HTN, exercise
How much is IRV relative to TV?
IRV = 5x of TV
How much is ERV relative to TV?
ERV = 2-2.5x of TV
What is inspiratory capacity (IC)?
TV + IRV
What is functional residual capacity (FRC)?
RV + ERV
What is vital capacity (VC)?
TV + IRV + ERV
all the air going in & out
What is forced expiratory volume in 1 sec (FEV1)?
the volume of air exhaled in the first second under force after max inhalation
What is forced vital capacity (FVC)?
the total volume of air that can exhaled during a max forced expiration effort
What are pulmonary function tests (PFTs)?
series of breathing tests to evaluate lung function
helps dx & manage lung conditions like COPD & restrictive lung disease
What are the characteristics of obstructive diseases?
What are some common conditions?
no problems inhaling, but air does not come out when exhaling (air trapping)
increased RV, FRC, TLC
decreased IRV, ERV, IC, VC FVC, FEV1
TV remains normal
cystic fibrosis, bronchitis, asthma, bronchiectasis, emphysema (CBABE)
What is the GOLD classification for COPD?
FEV1/FVC for all is <70%
mild COPD:
FEV1: ≥80% predicted
w/ or w/o production of cough & sputum
moderate COPD:
FEV1: 50-80% predicted
SOB w/ exertion
w/ or w/o production of cough & sputum
severe COPD:
FEV1: 30-50% predicted
greater SOB w/ exertion, reduced exercise capacity, fatigue
repeated exacerbation of their disease
very severe COPD:
FEV1: <30% predicted, or <50% predicted + chronic respiratory failure
respiratory failure
signs of R HF (cor-pulmonale)
How can you treat pts w/ obstructive lung disease?
improve airflow clearance and avoid early airway closure:
pursed lip breathing
huffing instead of coughing
What are the characteristics of restrictive diseases?
What are some common conditions?
less air coming in & out
decreased everything, except for FEV1 which stays normal
interstitial lung disease (ILD), sarcoidosis, lung fibrosis, scoliosis, kyphosis, ankylosing spondylitis, ALS, obesity, burns, PNA, pneumothorax, hemothorax, pulmonary effusion
How can you treat pts w/ restrictive lung disease?
address underlying cause:
ventilatory support
respiratory mm training/chest expansion exercises
What are the normal breath sounds?
vesicular
broncho-vesicular
bronchial
tracheal
the further down the lungs you go, the lower the sound
What are the characteristics of vesicular breath sounds?
Where can it be found?
softest intensity, lowest pitch of expiration
inspiratory longer than expiratory
over most of the lungs
What are the characteristics of broncho-vesicular breath sounds?
Where can it be found?
medium intensity & pitch of expiration
inspiratory & expiratory sounds equal in length (similar to tracheal)
b/w 1st & 2nd IC spaces anteriorly, b/w scapulae posteriorly
What are the characteristics of bronchial breath sounds?
Where can it be found?
loud intensity, high pitch of expiration
expiratory longer than inspiratory
over manubrium
What are the characteristics of tracheal breath sounds?
Where can it be found?
loudest intensity, relatively high pitch of expiration
inspiratory & expiratory sounds equal in length (similar to broncho-vesicular)
over trachea in the neck
What are the abnormal breath sounds?
rhonchi
wheeze
crackles (rales)
pleural rub
What are the characteristics of rhonchi?
Which conditions are associated with this?
continuous, low-pitched, rattling sound, like snoring
COPD, cystic fibrosis, chronic bronchitis, bronchiectasis, PNA
What are the characteristics of wheeze?
Which conditions are associated with this?
high-pitched, heard in expiration d/t airway obstruction (can be heard in inspiration in severe cases)
asthma, COPD, or aspiration of any foreign body
What are the characteristics of crackles (rales)?
What condition does this indicate?
brief, discontinuous, high-pitched, popping sounds heard in both inspiration & expiration
pulmonary edema
What are the characteristics of pleural rub?
What condition does this indicate?
auscultation of lower lateral chest w/ each inspiration & expiration
pleural inflammation
What is bronchophony?
What causes this?
increased vocal resonance w/ greater clarity & loudness of spoken words
secretions in lungs
What is egophony?
What causes this?
long “E” sounds ∆ to a long, nasal-sounding “A” sound
secretions in lungs
What is whispered pectoriloquy?
What would you have the pt say to test this?
increased loudness of whispering
recognition of the whispered words “one, two, three”