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Why did circulatory systems evolve?
Diffusion became too slow in larger organisms
What limits diffusion?
Distance and thickness
What do circulatory systems transport?
Oxygen, nutrients, waste
What are capillaries?
Thin blood vessels for exchange
Why are capillaries one cell thick?
To maximize diffusion
To maximize diffusion
Slows down
Why is slow flow important?
Allows more exchange time
What do simple organisms use instead of circulatory systems?
Diffusion / gastrovascular cavity
Why did the heart evolve?
To generate pressure to move blood
What is cardiac muscle specialized for?
Coordinated contraction
What are intercalated discs?
Connections between heart cells
What is an open circulatory system?
Blood directly contacts tissues
What is a closed circulatory system?
Blood stays in vessels
Which system is more efficient?
Closed
How many chambers does a fish heart have?
2
How many chambers does an amphibian heart have?
3
How many chambers do mammals have?
4
What is the septum?
Wall separating heart chambers
What is double circulation?
Two circuits (pulmonary + systemic)
arteries
carry blood away from heart, high pressure
veins
carry blood back to the heart, low pressure
ventricle
pump blood out
atria
recieve blood
right atrium
from body
left atrium
from lungs
right ventricle
to lungs l
left ventricle
to body
what ventricle is the thickest?
left ventricle because it pumps blood to entire body (highest pressure)
pulmocutaneuous
combinations of using skin and lungs for gas exchange, only seen in amphibians
What is double-loop circulation?
Blood passes through the heart twice per cycle
What are the two circuits?
Pulmonary and systemic
What is the function of the pulmonary circuit?
Gas exchange
What is the function of the systemic circuit?
Deliver oxygen and nutrients
Why is double-loop circulation efficient?
Separates oxygenated and deoxygenated blood
pulmonary circuit
Blood flow between heart and lungs
Where does pulmonary circulation start?
Right ventricle
Where does it end?
Left atrium
What happens in the lungs?
Gas exchange (O₂ in, CO₂ out)
Which artery carries deoxygenated blood?
Pulmonary artery
Which vein carries oxygenated blood?
Pulmonary vein
What is the systemic circuit?
Blood flow between heart and body
Where does it start? systematic circuit
Left ventricle
Where does it end? systematic circuit
Right atrium
What does systematic circuit remove?
CO₂ and waste
What is the main artery in systemic circulation?
Aorta
What is arterial blood?
Oxygen-rich blood
What is venous blood?
Oxygen-poor blood
What does arterial blood deliver?
Oxygen and nutrients
What does venous blood carry?
Carbon dioxide and waste
Where does venous blood go?
Back to the heart
Which system flips oxygen levels?
Pulmonary system
What are the main components of blood?
Plasma and cells
What does plasma do?
Transports substances
What do red blood cells do?
Carry oxygen
What do white blood cells do?
Fight infection
What do platelets do?
Clot blood
Where are blood cells made?
Bone marrow
What is the stem cell for blood cells?
Hemocytoblast
What is a lineage?
A developmental pathway of cells
What is the myeloid lineage?
Produces RBCs, platelets, and many WBCs
What is the lymphoid lineage?
Produces lymphocytes
What cells come from lymphoid lineage?
B cells, T cells, NK cells
What is systole?
Contraction of the heart
What is diastole?
Relaxation of the heart
What do valves do?
Prevent backflow which is blood flowing in the wrong direction
Where is pressure highest?
Aorta
Why does pressure drop?
Friction + branching
Why does blood slow in capillaries?
Increased cross-sectional area
Why is slow flow important?
Allows exchange
What helps veins return blood?
Valves
What prevents backflow?
Valves
What is cross-sectional area?
Total area of vessels
What happens when cross-sectional area increases?
Flow slows down
What is atherosclerosis?
Plaque buildup in arteries
What happens to the lumen in atherosclerosis?
It narrows
What are foam cells?
Macrophages filled with cholesterol
What does reduced blood flow cause?
Less oxygen to tissues
What can blockage in the heart cause?
Heart attack
What can blockage in the brain cause?
Stroke
Arteriosclerosis
Artery stiffens (hardening)
What does an ECG measure?
Electrical activity of the heart
Who invented the first ECG method?
Augustus Waller
What does the P wave represent?
Atrial contraction
What does the QRS complex represent?
Ventricular contraction
What does the T wave represent?
Heart relaxation
What does the lymphatic system do?
Fluid balance + immune defense
What fluid does the lymphatic system carry?
Lymph
Does the lymphatic system have a pump?
No
How do the systems work together? lymphatic system and circulatory
Lymph returns excess fluid to blood
gastrovascular cavity
A single-opening digestive compartment
What fluid is in an open system?
Hemolymph
What fluid is in a closed system?
Blood
what is hemolympth
blood and other other fluids found in an open circulatory system
Which animals have open circulatory systems?
Arthropods and most mollusks
How do insects get oxygen?
Tracheal system
Do amphibians have mixing of blood?
Yes
pulmocutaneous circuit
to lungs and skin
systemic circuit
to body
what is the biggest difference in between reptile blood circuits and reptile blood circuits?
Better separation of blood than amphibians, but not perfect, they have incomplete septum (flap of tissue)