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I blood group

Pathogenic autoanti-I
I Blood group Abs
associated with cold agglutinin syndrome
Primary Atypical Pneumonia (Mycoplasma pneumoniae)
High titer reactivity at 4*C
Reacts over wide thermal range (30- 32*C)
Anti-I
I Blood group Abs

Anti-i
I Blood group Abs

P1 Antigen

Anti-P1
“P” Blood Group Abs

Anti-Tja
“P” Blood Group Abs

autoanti-P
“P” Blood Group Abs

anti-P1
“P” Blood Group

P antigen
“P” Blood Group

anti M and anti N
MNSs Blood Group
reported in 1927 by Landsteiner and Levine
S
MNSs Blood Group
discovered by Walsh and Montgomery in 1947
s
MNSs Blood Group
discovered in 1951
U
MNSs Blood Group
universal; named by Weiner in 1953
46
MNSs Blood Group
There are ____ Ag that are expressed by the MNSs blood group system.
GYPA
MNSs Blood Group :Genetics

MNSs Blood Group : Genetics

GPA
MNSs Blood Group : Genetics

antithetical
MNSs Blood Group : Genetics

GBP
MNSs Blood Group : Genetics

glycophorin B
MNSs Blood Group

glycophorin A
MNSs Blood Group

anti-M
MNSs Blood Group Ag

Anti N
MNSs Blood Group Ag

Anti-S and Anti-s
MNSs Blood Group Ag

U phenotype
MNSs Blood Group Phenotype

Mk phenotype
MNSs Blood Group Phenotype

Kell Blood Group

Anti K
Kell Blood Group Ag

mcleod phenotype
Kell Blood Group Phenotype
X-linked inheritance: Males are affected
RBCs are acanthocytic in nature
WBCs of patients are deficient in enzyme (NADH-oxidase)
associated with CGD (Chronic Granulomatous Disease)
________Syndrome: variety of muscle and nerve disorders
RBCs lack Kx and Km
Kx antigen
Other Kell Phenotypes

Ko phenotype and Anti-Ku
Other Kell Phenotypes
Note: This particular blood group is one of the perfect examples in which the Abs or Ag develop, must be destroyed, because these particular Abs can cause HDN and HTR.

Duffy Blood Group

Fya, Fyb Antigens
Duffy Blood Group Ag

FyX
Duffy Blood Group

anti fya and anti fyb
Duffy Blood Group Abs

Anti fy3
Duffy Blood Group Abs

Kidd Blood Group

Kidd Blood Group Antibodies

Anti-Jka and Anti-Jkb
Kidd Blood Group Abs

Jk null phenotype
Kidd Blood Group Phenotype

anti Jk-3
Kidd Blood Group Abs

Aua and Aub antigens
Lutheran Blood Group Ag

Anti-Lua
Lutheran Blood Group Abs

Anti-Lub
Lutheran Blood Group Abs

Lu (a-b-)
Lutheran Blood Group Phenotype
loose-mixed field agglutination pattern
