Benzene Substituents: Reactivity and Directing Effects

A set of flashcards categorizing common benzene substituents as meta-directing deactivators, ortho/para-directing deactivators, or ortho/para-directing activators.

$$-NO_2$$

A meta-directing deactivator.

$$-SO_3H$$

A meta-directing deactivator.

$$-COH$$

A meta-directing deactivator.

$$+NR_3$$

A meta-directing deactivator.

$$-C \equiv N$$

A meta-directing deactivator.

$$-COCH_3$$

A meta-directing deactivator.

$$-COOCH_3$$

A meta-directing deactivator.

$$Br$$

An ortho- and para-directing deactivator.

$$-H$$

The reference point (Benzene) for reactivity.

$-CH_3$ (alkyl)

An ortho- and para-directing activator.

$$-NH_2$$

An ortho- and para-directing activator.

$$-NHCOCH_3$$

An ortho- and para-directing activator.

$$-OH$$

An ortho- and para-directing activator.

Benzen

An ortho- and para-directing activator.

$$OCH3$$

An ortho- and para-directing activator.

$$-F$$

An ortho- and para-directing deactivator

$$-I$$

An ortho- and para-directing deactivator

$$-Cl$$

An ortho- and para-directing deactivator.

$$-COOH$$

Meta-directing deactivator.