Glutamate 5 - Postsynaptic Mechanisms

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Last updated 6:59 AM on 5/19/26
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8 Terms

1
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Ionotropic Glutamate Receptors

Fast

2
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AMPA Receptor

A synthetic amino acid-named ionotropic receptor that mediates the majority of fast

3
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Kainate Receptor

An ionotropic receptor named after a seaweed component that causes excitation by opening Na+ and Ca2+ channels.

4
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NMDA Receptor

A unique ionotropic receptor that allows Na+ and Ca2+ influx and triggers secondary messenger cascades.

5
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NMDA Coincidence Detector

Requires a "double-hit" of simultaneous presynaptic glutamate release and postsynaptic depolarization to open.

6
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Magnesium (Mg2+) Plug

The ion that physically blocks the NMDA channel pore at resting potential due to strong electrical attraction.

7
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NMDA Activation Mechanism

AMPA channels open allowing Na+ influx

8
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Metabotropic Glutamate Receptors (mGluRs)

Slower