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phospholipid
Head= hydrophilic (polar)
tail= hydrophobic (non-polar); fatty acids
Both create a barrier for things to not get through
why we need phospholipids
To protect it from environment
Selective permeability
Ability to pass through
Certain things can get through or not
Extracellular matrix
Everything outside the cell
electrical gradient
Both sides of the membrane have different electrical charges
Electrical potential
When channels open there is potential for action, communication, etc
chemical gradient
More on the outside vs inside
Chemical potential
When certain doors open, things can happen
the difference in the concentration of a chemical substance between two areas
membrane proteins functions
Make it dynamic
Pass things in and out
Transport stuff
Attach to neighbors
Attach to extracellular (outside the cell) matrix (structure)
Bone cell lives inside an extracellular matrix
marker molecules (membrane protein)
Allow cells to identify other cells or other molecules
Ex: glycoprotein
attachment proteins (membrane proteins)
Anchor cells to other cells (cadherins) or to extracellular molecules (integrins)
Ex: skin cells
channel proteins
Form passageways through the plasma membrane, allowing specific ions or molecules to enter or exit the cell; may be leak or gated
leak channel
Always open
Responsible: permeability of plasma membrane
Always allows potassium ions to move through the gradient (a higher concentration to a lower concentration)
gated ion channels
Open or close by certain stimuli (in response to chemical or electrical signals)
Need something attached to it to open the gate
carrier proteins (transporters)
Move ions or molecules across the plasma membrane; binding of specific chemicals to carrier proteins causes changes in the shape of the carrier proteins. The carrier proteins then move to the specific chemical across the plasma membrane.
ATP-powered pumps
Move specific ions or molecules across the plasma membrane; require ATP molecules to function
Must use energy to be useful
receptor proteins
Function as binding sites for chemical signals in the extracellular fluid; binding of chemical signals to receptors triggers cellular responses
tihngs that can pass through easily through a cell membrane
Lipids (O2, CO2)
Easily able to dissolve
passive transport
The cell does not extend ATP; movement of substance from higher concentration to lower concentration
Diffusion, osmosis, facilitated diffusion
active membrane transport
ATP used to move substance from lower concentration to higher concentration
Active transport, secondary active transport
vesicular transport
Involves a membrane-bound sac (vesicle)
Endocytosis and exocytosis
diffusion
High concentration of substance that allows itself to dissolve (to an area of lower concentration)
Becomes an equilibrium solution
osmosis
Diffusion of water across a selective permeable membrane
hypertonic
cell shrinks b/c red blood cell loses water
isotonic
same amount of salt inside the water as the outside
hypotonic
cell gets bigger because it gains water
facilitated diffusion
1. A glucose molecule enters a carrier protein from the extracellular fluid. The glucose binds to the carrier protein
2. The carrier protein changes shape and releases the glucose molecule into the cell. The carrier protein then resumes its original shape to transport additional glucose molecules.
active transport
Needs ATP
Substance moved against their concentration gradient (from low to high), allowing the substance to accumulate on one side of the plasma membrane
Sodium,-potassium pump
a vital membrane protein that uses energy from ATP to move three sodium ions out of the cell and two potassium ions into the cell
secondary active transport
Use of potential energy in concentration gradient of one substance to help move another substance against its gradient
Allows sodium and glucose to go in the cell
vesicular transport
Requires ATP
Movement of larger substances by formation or release of a vesicle
Endocytosis
movement into cell
phagocytosis
pinocytosis
phagocytosis
Solid particle is ingested and large vesicle is formed
Create an opening and wrap itself around the particle, pinch itself off, and eat the particle
pinocytosis
Dissolved molecules ingested and small vesicles are formed
a cellular process known as "cell drinking," where a cell engulfs small drops of extracellular fluid and dissolved nutrients
exocytosis
Movement out of cell
Secretion