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Lateral plate mesoderm splits into
Parietal and visceral mesoderm
intraembryonic cavity
Space between mesoderm layers
Splanchnopleure is formed from
Endoderm and visceral mesoderm
Splanchnopleure becomes future
Gut and gut derivatives
Somatopleure comes from
Ectoderm and parietal mesoderm
Somatopleure becomes future
Ventral body wall
Vitelline duct
Connection between yolk sac and foregut
Amnion grows eliminating
Chorionic cavity
Dorsal messers develops from
Splanchnic mesoderm
Primary bronchial buds become future
Main bronchi
Esophageal atresia
Defect in foregut partitioning
Tracheoesophageal fistula
Defect in tracheoesophageal septum
Congenital diaphragmatic hernia
Defect of pleuroperitoneal folds (they don’t close)
Pulmonary hypoplasia
Underdeveloped lungs
Respiratory distress syndrome
Premature babies, surfactant deficiency (type 2)
Septum transversum function and future
Separates thoracic from abdomen, future diaphragm
Pericardioperitoneal canals future
Pleural cavities
Pleuropericardial folds separates
Pleural cavity from mediastinal pleura
Pleuroperitoneal folds close
Pericardioperitoneal canals
Respiratory tract conducting portion
Specialized for transporting air
Respiratory tract respiratory portion
For gas exchange, includes bronchioles and alveoli
Mucociliary apparatus
Nasal traps, naso/oropharynx have lymphoid structures
Respiratory epithelium
Pseudostratified ciliated columnar
Clara cells are found
In bronchioles
Clara cells functions
Neutralize toxins, secrete surfactant, differentiate into other tissues
Type 1 pneumocytes
Squamous cells for gas exchange
Type 2 pneumocytes
Epithelial cells secrete surfactant
Goblet cells function
Produce mucus
Alveolar macrophages function
Cleanup unwanted debris
Where do you find pneumocytes
Alveoli
Neuroendocrine cells functions
Secrete serotonin that regulates mucus production and cilia motility
Basal cells
Multipotent
Lung stages mnemonic
Every pro can sac Aaron