Key points for non-progressive brain injury + progressive conditions

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12 Terms

1
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Non-progressive brain injuries (5)

  • TBI

  • Stroke

  • Encephalitis

  • Anoxia

  • Epilepsy


2
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Progressive conditions

  • Dementia

  • MS

  • Parkinson’s

  • HD

  • Brain tumour


3
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TBI: def, assessment name (1), sequelae (2), int. (1)

  • Structural + functional changes to brain arising from mechanical blow


  • Glasgow Coma Scale (GCS)


  • Cog. deficits

    • Including exec dys.

  • Emotional changes


  • Focus on functional compensation


4
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Stroke: def, assessment (1), sequelae (1→2, 1→2) , int. (3)

  • Disease of blood vessels supplying the brain


  • Cog. assessment should be done early


  • Cog. impairment

    • Exec function

    • Language

  • Psych consequences

    • Depression

    • Anxiety


  • Cog. rehab

  • Compensatory strats

  • Psychotherapy


5
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Encephalitis: def, assessment, sequelae (1→2, 1→2), int. (treatment) (2)

  • Inflammation of brain tissue


  • Diagnosis of exclusion (patient history, brain imaging etc.)


  • Cog.

    • Reduced IQ

    • Exec dysfunction

  • Emotional + psych

    • Depression

    • Anxiety


  • Let virus run course or antivirals/bacterials/fungals (infectious)

  • Immune-modulatory treatments or removal of tumour (if this is the cause) (autoimmune)



6
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Anoxia: def, sequelae (5), int. (1 w example)

  • Reduced or restricted O2 supply to the brain


  • Cog.

    • Exec. dys.

    • Memory deficits

  • Emotional

    • Depression

    • Anxiety

  • Visuospatial/perceptual

  • Severe intellectual impairment

  • DOC


  • Holistic approach

    • E.g. memory aids


7
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Epilepsy: def, sequelae (1), int. (5)

  • Characterised by unprovoked + recurrent seizures


  • Cog. deficits


  • Work systematically through issues

    • Optimise seizure control

    • Optimise psychiatric state

    • Acceptance of cog. deficits

    • Set goals using SOS framework

      • Strategies, outsourcing, social support

    • Monitor + evaluate


8
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Dementia: def, presentations based on type (3), assessment (3), intervention/rehab: theory (2), practice (2)

  • Umbrella term for neurodegenerative disorders which result in progressive cognitive decline


  • Memory deficits (Alzheimer’s + vascular)

  • Behavioural changes (frontotemporal)

  • Lang. impairment (semantic


  • MMSE, observation, neuroimaging etc.


  • Enablement philosophy

  • Individualised + goal-oriented rehab

  • GREAT program

    • Action-based procedural learning

    • Environmental restructuring



9
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MS: def, presentations (1, 1→2, 1), int.

  • Progressing CNS condition arising from irrecoverable loss of myelin, leading to axonal damage + grey matter loss


  • Motor

  • Cog. (not predicted by disease course/severity)

    • Reduced processing speed

    • Attention

  • Psych.


  • Attention + memory retraining (more research needed)


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PD: def, presentations (1→3, 1→2, 1→3), , int. (1→2, 1→1)

  • Loss of dopaminergic cells in substantia nigra


  • Motor

    • Tremor

    • Muscle rigidity

    • Gait difficulties

  • Cog.

    • Early PD: frontostriatal deficits (attention + exec)

    • Advanced PD: ^^ + memory deficits

  • Psychiatric

    • Depression

    • Anxiety

    • Apathy


  • Pharmacological

    • Cholinesterase inhibitors for PDD

    • No pharmacological int. yet MCI or prevention

  • Non-pharmacological

    • Usual + exergaming


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HD: def, presentations (1→2, 1→3, 1→2), int. (2)

  • Hereditary autosomal dominant disorder leading to degeneration of striatum


  • Motor

    • Chorea

    • Bradykinesia

  • Cog.

    • Psychomotor slowing

    • Exec. dysfunction

      • Multitasking

    • Memory

      • Retrieval failure (not amnesia)

  • Social + affective

    • Impaired social cognition (emotion rec., ToM)

    • Apathy


  • External cueing (for apathy)

  • Simplify tasks to avoid multitasking


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Brain tumours: def, presentations (1→2, 1→2, 1→2), int. (1, 1→1)

  • Abnormal group of cells in the brain or meninges


  • Cog. (from tumour focal impact + radiotherapy neurotoxicity)

    • Exec.

    • Memory

  • Behavioural

    • Apathy

    • Inappropriate behaviour

  • Psychiatric

    • Depression

    • Death anxiety (patient + carers)


  • Cog. rehab

  • Multidisciplinary community-based approach

    • Making Sense of Brain Tumours Program home-based psychotherapy + rehab (existential stress etc.)